Welcoming you for any type of article submission for the upcoming issue on/before January 17, 2023.

EC Pharmacology and Toxicology

EC Pharmacology and Toxicology (ECPT) is an internationally peer reviewed journal that desires to publish articles on all aspects of Pharmacology and Toxicology. The journal aims to publish clinical and experimental work on all the topics related to Pharmacology and Toxicology. The main motto of ECPT is to bring latest developments and current research in Pharmacology and Toxicology into light by publishing quality and original articles. We deal with all aspects of Pharmacology and Toxicology that mainly involves diagnosis of diseases and therapeutic interventions including interactions of chemical substances with living systems, with a view to understanding the properties of drugs and their actions, including the interactions between drug molecules and drug receptors and how these interactions elicit an effect.

Aim and scope

Pharmacology and toxicology are at the forefront of modern medicine, designing, developing and testing drugs that have the potential to alleviate, and in some cases cure the diseases that afflict humans and animals. Today, both clinical and basic research is has become most essential. Scientific research is also taking place to look for causes and possible treatment in diseases. Pharmacology provides the scientific basis and principles for a variety of special applications, such as the study of drug actions in the health sciences, the use of drugs as therapeutic agents in medicine or as tools in scientific research, and the development and regulation of pharmaceuticals. Pharmacology is a multi-disciplinary science with many subspecialties including clinical pharmacology, cardiovascular pharmacology, behavioural pharmacology, neuropsychopharmacology, pharmacogenetics, and pharmacoeconomics, to name a few. Toxicology is the study of the adverse effects of chemicals (including drugs) on living systems and the means to prevent or ameliorate such effects. In addition to therapeutic agents, toxicologists examine many environmental agents and chemical compounds that are synthesized by humans or that originate in nature. The toxic effects of these agents may range from disturbances in growth patterns, discomfort, disease or death of individual organisms or on whole ecosystems. There are many subspecialties of toxicology including: clinical toxicology, regulatory toxicology (both of these found in the pharmaceutical and toxicology industry), forensic toxicology, occupational toxicology, and risk assessment. Advancements in the field of Pharmacology and Toxicology Research play a major role in building a safe and healthy society.

ECPT accepts articles on all the topics related to Pharmacology and Toxicology such as Behavioral Pharmacology, Cardiovascular Pharmacology, Biochemical and Cellular Pharmacology, Chemotherapy, Drug Discovery, Drug Development, Drug Metabolism and Disposition, Endocrine Pharmacology, Neuropharmacology, Molecular Pharmacology, Pharmacology Education, Systems and Integrative Pharmacology, Toxicology, Therapeutics, Veterinary Pharmacology, Environmental Toxicology and Pharmacology, Clinical Pharmacology, Cardiovascular Pharmacology, Pharmacotherapeutic Trials, Animal Pharmacology, Comparative Pharmacology, Pharmacoepidemiology Studies, Chemotherapy Drugs, Pharmacodynamics Interactions, Adverse Reaction, Drug Screening, Clinical Trial, Forensic Toxicology, Environmental Toxicology, Reproductive Toxicity, Toxicological Screening, Medical Pharmacology for Health Sciences, Basic Mechanisms of Drug Action, Cardiovascular Pharmacology, Advanced Research Techniques in Pharmacology, Forensic Toxicology, Toxicogenomics, Toxicology of Natural Products, Signaling Pathways in Functional Cells, Drug Design and Drug-Drug Interaction, Chemotherapy, Toxicology, Environmental Toxicology, Pulmonary Irritants, Aerosols, Drugs for Respiratory Disorders, Antifungal, Antiviral, Antiprotozoal and Anthelmintic Drugs, Pharmacology for Health Sciences, Pharmacology of the Central Nervous System, Pedagogy in Pharmacology, Practical Problems in Biometry, Applications of Pharmacogenetics, Pharmacokinetics: Validation, Metabolism, Immunopharmacology and Immunotoxicology, Radio Chemicals and Radiopharmaceuticals, Drug Delivery and Metabolism, Proteomics and Metabolomics, Hepatoxic, Nephrotoxic and Neurotoxic Agents, Pharmacology and its Therapeutics, Clinical Pharmacology, Clinical Pharmacy, Compounding Pharmacy, Drug Legislation and Safety, Environmental Pharmacology, Neuropharmacology, Nuclear Pharmacy, Pharmacoepidemiology, Pharmacogenetics, Pharmacogenomics, Pharmacognosy, Pharmacy Informatics, Psychopharmacology, Theoretical Pharmacology, Toxicology, Veterinary Pharmacy, Drug Discovery and Development, Molecular Pharmacology, Drug Metabolism, Mechanism of Action of Drugs, Drug Interactions, Experimental Animal Pharmacology and Toxicology, Toxicology, Pharmaceutical Sciences, Nanotoxicity, Safety Assessment of Drugs Including Natural Substances, Drug Induced Toxicity, Neurotoxicology, etc.

EC Pharmacology and Toxicology journal delightfully accepts articles in all the emerging areas of research in the field of Pharmacology and Toxicology at pharmacology@ecronicon.uk

Latest Articles

Guest Editorial

  • The Antidepressant Mirtazapine (MIRO), the Wonder Drug Applied in the Confrontation with the Traumatic Effects of Battle. Post-Traumatic Stress Disorder
  • Shimon Shatzmiller. 10(9): 01-05.

    Research Article

  • Cardioprotective Effect of -(4'-Methoxyphenyl)-6,7- Dimethoxy-1,2,3,4-Tetrahydroisoquinoline
  • Sadriddin N Boboev, Inoyat Z Jumayev, Pulat B Usmanov and Sherzod N Zhurakulov. 10(9): 15-20.

    Review Article

  • Basics of Machine Learning in Drug Discovery: A Bird’s Eye Perspective
  • Rekha Choudhary, Pranali Yelchatwar, Vinayak Walhekar, Ashwini Patil, Dileep Kumar, Amol Muthal, Macha Baswaraju, Garige Anil kumar, Chandrakant Bagul and Ravindra Kulkarni. 10(9): 21-45.

    Review Article

  • Bioactivity and the Prospect of Stelechocarpus burahol as Oral Deodorant
  • Maksum Radji. 10(9): 46-53.

    Review Article

  • Pharmacotherapy of Ovulatory Dysfunctional Uterine Bleeding: An Update Review
  • Suhui Lou and Junzheng Yang. 10(9): 54-57.

    Review Article

  • Pharmacological Activity of Dawa-ul-Kurkum
  • Mohd Rafi Reshi, Kavita Gulati and Arunabha Ray. 10(9): 58-68.

    Review Article

  • Evaluation of In Vivo Teratogenic Effect of Ocimum lamiifolium Hochst. Ex Benth. (Lamiaceae) and Zehneria scabra (Linn. f.) Sond. (Cucurbitacea) Leaves in Mice
  • Abel Andualem, Birhanu Geta Meharie and Yenesew Wudu. 10(9): 06-14.

    Research Article

  • Relationship between the Conservation of Medications and Virological Failure in HIV Positive Patients in a Health Care Institution at the Colombian Orinoquia and Amazonia
  • Orlando Angulo and Roberto Cardenas. 10(8): 49-58.

    Guest Editorial

  • Zoonotic Diseases and the Species Barrier
  • Shimon Shatzmiller, Galina Zats, Ludmila Buzhansky, Inbal Lapidot and Rami Krieger. 10(8): 44-48.

    Research Article

  • Piper nigrum Mitigates Reserpine-Induced Orofacial Dyskinesia in Wistar Rats
  • Rupali Arun Patil, Shubhangi Pawar and Sandeep D Sadafal. 10(8): 01-13.

    Research Article

  • Genotype Analysis of Single Nucleotide Variant in NCF4 and CBR3 Genes Associated with Reduced Systolic Fractional Shortening in Pediatric Patients with Acute Lymphoblastic Leukemia Treated with Doxorubicin
  • Jesús Alonso Gándara-Mireles, Ismael Lares-Asseff, Elio Aarón Reyes Espinoza, Javier G Blanco, Antonio Emilio González Font, Lourdes Patricia Córdova Hurtado, Verónica Loera-Castañeda, Ignacio Villanueva Fierro, Isaías Chairez Hernández, Hugo Payan-Gándara, Leslie Patrón Romero and Horacio Reyes-Almanza. 10(8): 14-25.

    Research Article

  • Examination of Dental Anxiety and Fear Levels of Dentistry Faculty Students: A Case of North Cyprus
  • Kübra Özsat, Mahdi Ghorbanı Mazraeh Khalafı, Hülya Şenol, Durmuş Aşıcıoğlu and Merve Karafistan. 10(8): 26-39.

    Short Communication

  • Pharmacotherapy and Drug Usage in Children
  • Charles D Shively. 10(8): 40-41.

    Short Communication

  • Controversial Views on Cancer
  • Shrihari TG. 10(8): 42-43.


  • Beta-Endorphinization and their Functioning in the Nervous System
  • Shrihari TG. 10(7): 25.

    Research Article

  • Pharmacological Evaluation of the Antidiabetic Effect of the Leaf Crude Extract of Hagenia abyssinica on Normoglycemic, Oral Glucose Loaded, and Streptozotocin-Induced Diabetic Mice; A Single Dose Study
  • Zemene Demelash Kifle, Yaschilal Muche Belayneh, Alem Endeshaw Woldeyohanin, Habtamu Assefa, Tesfaye Yimer and Dawit Kumilachew Yimenu. 10(7): 26-38.

    Research Article

  • Permeation, Bio-Distribution, and Subcellular Localization of Azulene Photosensitizer in Normal and Inflammatory Peripheral Blood Mononuclear Cells
  • Teerasak Damrongrungruang, Nujjakorn Yuhun, Arunroong Kuntiya and Patcharaporn Klaipithak. 10(7): 39-49.

    Review Article

  • Gut Dysbiosis and the Gut-Brain Axis
  • RE Carlson, V Koneru and JA von Fraunhofer. 10(7): 50-57.

    Letter to Editor

  • Antimicrobial Peptides in the Anticorona Combat
  • Shimon Shatzmiller, Galina Zats, Rami Krieger, Inbal Lapidot and Ludmila Buzhansky. 10(7): 58-61.


  • The Latest Orthopoxvirus Surge: Who Gets Monkeypox Next?
  • Charles D Shively. 10(7): 62-63.

    Short Communication

  • Phosphodiesterases: Biological Activities of Chemical Compounds that Antagonize these Enzymes
  • Chika J Mbah. 10(7): 64-68.

    Research Article

  • Cholinergic Agonists against Covid-19 in Humans. Results from a Randomized Open Label Pilot Trial
  • Jose-Gabriel Leon, Fabio Restrepo, Mario León, Mateo Politi, Fernando Mendive and Orlando Angulo. 10(7): 09-24.

    Review Article

  • Is there a Vaccine for HIV on the Horizon? What we've Learned thus Far from the Literature Review
  • Navpreet Singh, Harnoor Singh Sandhu, Naginder Pal Singh, Diljot Singh Bedi, Kanwar Shabaz Singh Sandhu and Avineet Kaur. 10(7): 01-08.

    Research Article

  • Prevalence of Indicators of Malnutrition and Associated Factors among Public Primary School Children in Hargeisa, Marodi Jeh Region, Somaliland, 2019.
  • Abdulkadir Mohamed Nuh, Melese Sinaga Teshome and Tefera Belachew. 10(6): 59-74.

    PubMed Indexed Article

    EC Pharmacology and Toxicology
    LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.

    PMID: 31143884 [PubMed]

    PMCID: PMC6536005

    EC Pharmacology and Toxicology
    Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.

    PMID: 31565701 [PubMed]

    PMCID: PMC6764777

    EC Neurology
    Differences in Rate of Cognitive Decline and Caregiver Burden between Alzheimer's Disease and Vascular Dementia: a Retrospective Study.

    PMID: 27747317 [PubMed]

    PMCID: PMC5065347

    EC Pharmacology and Toxicology
    Will Blockchain Technology Transform Healthcare and Biomedical Sciences?

    PMID: 31460519 [PubMed]

    PMCID: PMC6711478

    EC Pharmacology and Toxicology
    Is it a Prime Time for AI-powered Virtual Drug Screening?

    PMID: 30215059 [PubMed]

    PMCID: PMC6133253

    EC Psychology and Psychiatry
    Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.

    PMID: 30417173 [PubMed]

    PMCID: PMC6226033

    EC Anaesthesia
    Arrest Under Anesthesia - What was the Culprit? A Case Report.

    PMID: 30264037 [PubMed]

    PMCID: PMC6155992

    EC Orthopaedics
    Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.

    PMID: 30198026 [PubMed]

    PMCID: PMC6124505

    EC Pulmonology and Respiratory Medicine
    Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012.

    PMID: 30294723 [PubMed]

    PMCID: PMC6169793

    EC Dental Science
    Important Dental Fiber-Reinforced Composite Molding Compound Breakthroughs

    PMID: 29285526 [PubMed]

    PMCID: PMC5743211

    EC Microbiology
    Prevalence of Intestinal Parasites Among HIV Infected and HIV Uninfected Patients Treated at the 1o De Maio Health Centre in Maputo, Mozambique

    PMID: 29911204 [PubMed]

    PMCID: PMC5999047

    EC Microbiology
    Macrophages and the Viral Dissemination Super Highway

    PMID: 26949751 [PubMed]

    PMCID: PMC4774560

    EC Microbiology
    The Microbiome, Antibiotics, and Health of the Pediatric Population.

    PMID: 27390782 [PubMed]

    PMCID: PMC4933318

    EC Microbiology
    Reactive Oxygen Species in HIV Infection

    PMID: 28580453 [PubMed]

    PMCID: PMC5450819

    EC Microbiology
    A Review of the CD4 T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population

    PMID: 26280024 [PubMed]

    PMCID: PMC4533840

    EC Neurology
    Identifying Key Symptoms Differentiating Myalgic Encephalomyelitis and Chronic Fatigue Syndrome from Multiple Sclerosis

    PMID: 28066845 [PubMed]

    PMCID: PMC5214344

    EC Pharmacology and Toxicology
    Paradigm Shift is the Normal State of Pharmacology

    PMID: 28936490 [PubMed]

    PMCID: PMC5604476

    EC Neurology
    Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia

    PMID: 28713879 [PubMed]

    PMCID: PMC5510658

    EC Neurology
    Unilateral Frontosphenoid Craniosynostosis: Case Report and a Review of the Literature

    PMID: 28133641 [PubMed]

    PMCID: PMC5267489

    EC Ophthalmology
    OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling

    PMID: 29333536 [PubMed]

    PMCID: PMC5766278

    EC Neurology
    Longer Duration of Downslope Treadmill Walking Induces Depression of H-Reflexes Measured during Standing and Walking.

    PMID: 31032493 [PubMed]

    PMCID: PMC6483108

    EC Microbiology
    Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.

    PMID: 30957099 [PubMed]

    PMCID: PMC6448571

    EC Nutrition
    Food Insecurity among Households with and without Podoconiosis in East and West Gojjam, Ethiopia.

    PMID: 30101228 [PubMed]

    PMCID: PMC6086333

    EC Ophthalmology
    REVIEW. +2 to +3 D. Reading Glasses to Prevent Myopia.

    PMID: 31080964 [PubMed]

    PMCID: PMC6508883

    EC Gynaecology
    Biomechanical Mapping of the Female Pelvic Floor: Uterine Prolapse Versus Normal Conditions.

    PMID: 31093608 [PubMed]

    PMCID: PMC6513001

    EC Dental Science
    Fiber-Reinforced Composites: A Breakthrough in Practical Clinical Applications with Advanced Wear Resistance for Dental Materials.

    PMID: 31552397 [PubMed]

    PMCID: PMC6758937

    EC Microbiology
    Neurocysticercosis in Child Bearing Women: An Overlooked Condition in Mozambique and a Potentially Missed Diagnosis in Women Presenting with Eclampsia.

    PMID: 31681909 [PubMed]

    PMCID: PMC6824723

    EC Microbiology
    Molecular Detection of Leptospira spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.

    PMID: 31681910 [PubMed]

    PMCID: PMC6824726

    EC Neurology
    Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases.

    PMID: 31528859 [PubMed]

    PMCID: PMC6746603

    EC Psychology and Psychiatry
    Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?

    PMID: 31276119 [PubMed]

    PMCID: PMC6604646

    EC Anaesthesia
    Real Time Locating Systems and sustainability of Perioperative Efficiency of Anesthesiologists.

    PMID: 31406965 [PubMed]

    PMCID: PMC6690616

    EC Pharmacology and Toxicology
    A Pilot STEM Curriculum Designed to Teach High School Students Concepts in Biochemical Engineering and Pharmacology.

    PMID: 31517314 [PubMed]

    PMCID: PMC6741290

    EC Pharmacology and Toxicology
    Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese.

    PMID: 31633124 [PubMed]

    PMCID: PMC6800226

    EC Neurology
    Research Volunteers' Attitudes Toward Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.

    PMID: 29662969 [PubMed]

    PMCID: PMC5898812

    EC Pharmacology and Toxicology
    Hyperbaric Oxygen Therapy for Alzheimer's Disease.

    PMID: 30215058 [PubMed]

    PMCID: PMC6133268

    News and Events

    February Issue Release

    We always feel pleasure to share our updates with you all. Here, notifying you that we have successfully released the February issue of respective journals and the latest articles can be viewed on the current issue pages.

    Submission Deadline for Upcoming Issue

    ECronicon delightfully welcomes all the authors around the globe for effective collaboration with an article submission for the upcoming issue of respective journals. Submissions are accepted on/before February 17, 2023.

    Certificate of Publication

    ECronicon honors with a "Publication Certificate" to the corresponding author by including the names of co-authors as a token of appreciation for publishing the work with our respective journals.

    Best Article of the Issue

    Editors of respective journals will always be very much interested in electing one Best Article after each issue release. The authors of the selected article will be honored with a "Best Article of the Issue" certificate.

    Certifying for Review

    ECronicon certifies the Editors for their first review done towards the assigned article of the respective journals.

    Latest Articles

    The latest articles will be updated immediately on the articles in press page of the respective journals.