Case Report
Volume 3 Issue 3 - 2020
Efficacy of Aloe Fermented Butyrate to Autism Spectrum Disorders
Megumi Hasegawa1, Akira Yagi2* and Suzuka Ataka3
1Pharmacist, Kampo Pharmacy Grace-Meg-Salon, Toshima-ku, Tokyo, Japan
2Professor Emeritus, Fukuyama University, Hiroshima, Japan
3Department of Neurology, Osaka City University Medical School, Part-Time Lecturer, Med Cell Clinic Osaka, Kita-ku, Umeda, Osaka, Japan
*Corresponding Author: Akira Yagi, Professor Emeritus, Fukuyama University, Hiroshima, Japan.
Received: January 29, 2020; Published: February 26, 2020


Butyrate is a metabolite of short chain fatty acid by the gut microbiota in large intestine. Butyrate is main energy source for enterocyte regeneration and modulates the enteric microbial community and contributes to impact on intestinal health and host well-being with its beneficial activity in inflammation and neurological disorders. The gut microbiome has played a crucial role in the multi-directional gut-brain axis that integrates the gut and central nerve system activities, and thus a concept of microbiome-gut-brain axis is emerging. In this review, we describe the putative efficacy of gut butyrate to autism spectrum disorders (ASD) and exhibit a case report of ASD patient with aloe vera juice adjuvant.

Keywords: Immune Modulation; Endophytically Fermented Aloe Butyrate; Microbiome-Gut-Brain Axis; Autism Spectrum Disorders; A Case Report


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Citation: Akira Yagi., et al. “Efficacy of Aloe Fermented Butyrate to Autism Spectrum Disorders”. EC Clinical and Medical Case Reports 3.3 (2020): 01-09.

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