Literature Review
Volume 4 Issue 1 - 2021
Mesenchymal Chondrosarcoma of Cervical Vertebrae: Clinical Experience with Review of Literature
Sufian Zaheer1* Navpreet Kaur2 and Sunil Ranga3
1Pathology, Professor, VMMC and Safdarjang, Hospital, Delhi, India
2Pathology, Senior resident, VMMC and Safdarjang Hospital, Delhi, India
3Pathology, Professor, VMMC and Safdarjang, Hospital, Delhi, India
*Corresponding Author: Sufian Zaheer, Pathology, Professor, VMMC and Safdarjang, Hospital, Delhi, India.
Received: December 11, 2020; Published: December 30, 2020


Mesenchymal chondrosarcoma (MCS) is a rare but aggressive variant of conventional chondrosarcoma, which carries a poor prognosis. Only a few cases of such tumors originating from the spinal vertebrae have been described in the literature. It usually occurs in teenagers and young adults, but the peak is seen in the second and third decade. Jaw bones especially the mandible is commonly involved. We report here a case of a 17-year boy who presented with pain and swelling in the left side of the neck, along with weakness of the left upper limb. On CECT left side of the arch of the atlas, bone showed osteolytic destruction. There was involvement of C2, C3, and C4 vertebrae. MRI showed a large paravertebral mass with areas of focal calcification. On aspiration plump oval to spindle cells were seen. Histopathological examination of the biopsy material revealed the characteristic biphasic pattern of MCS. We suggest the differential diagnosis of every primary vertebral tumor to include the tumors of mesenchymal origin.

Keywords: Mesenchymal Chondrosarcoma; Cervical Vertebrae; Clinical Experience; Review of Literature


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Citation: El Sufian Zaheer., et al. “Mesenchymal Chondrosarcoma of Cervical Vertebrae: Clinical Experience with Review of Literature”.EC Clinical and Medical Case Reports 4.1 (2021): 27-32.

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