Research Article
Volume 7 Issue 5 - 2020
Usefulness of Carotid Ultrasound in Patients with Intermediate Pretest Probability of Coronary Artery Disease
Ahmad Abdelaziz1, Ragab A Mahfouz2 and Ghada A Kazamel1*
1Cardiology Department, National Heart Institute, Egypt
1Cardiology Department, Zagazig University Hospital, Egypt
*Corresponding Author: Ghada A Kazamel, Cardiology Department, National Heart Institute, Egypt.
Received: April 13, 2020; Published: April 30, 2020




Abstract

Objective: We aimed to investigate the clinical significance of carotid ultrasound in subjects with chest pain had intermediate pretest probability of CAD.

Methods: Eighty consecutive patients presented with chest pain and had intermediate pretest probability for CAD were subjected to carotid intima media thickness (CIMT) and carotid plaque evaluation with the use of carotid ultrasound. The presence and evaluation of CAD was performed with CCTA.

Results: 37% of the study cohort had CCTA documented. Of patients with CCTA documented coronary stenosis > 50%, the CIMT was significantly higher (p < 0.001). Furthermore, the calcium score was significantly higher in those with obstructive CAD (p < 0.005). Multivariate analysis demonstrated that increased CIMT was associated with an increased risk of coronary stenosis > 50% (odds 1.56 [1.22 - 1.93], p < 0.03), whilst carotid plaque thickness was associated with coronary stenosis (odds ratio 2.85 [1.25 - 3.72], p < 0.001) after adjusting for traditional risk factors. ROC analysis showed that the best cutoff CIMT value for predicting CAD was 0.89 mm, while the cutoff value of plaque thickness was 1.95 mm.

Conclusion: Carotid plaque and CIMT were significantly associated with coronary plaque burden in subjects presented with chest pain and had intermediate pretest probability of CAD. Thus, we suggest that carotid ultrasound might provide a useful noninvasive tool for risk stratification of subjects presented with acute chest pain and deemed to have intermediate pretest probability of CAD.

Keywords: Carotid Ultrasound; Coronary Plaque Burden; Coronary CT Angiography

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Citation: Ghada A Kazamel., et al. “Usefulness of Carotid Ultrasound in Patients with Intermediate Pretest Probability of Coronary Artery Disease”. EC Cardiology 7.5 (2020): 82-91.

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