Research Article
Volume 7 Issue 12 - 2020
Early Prediction of Myocardial Viability Following Acute Myocardial Infarction by Two-Dimensional Speckle Imaging
Mohamed Abdelmonem Aboutaha*, Neama Ali Elmeligy, Azza Ali Katta, Osama Sanad Arafa, Mohamed El Bordy, Mohamed Samir Hamada, Hany Abd El Salam Basiouny and Mohamed Mahrous Ali
Department of Cardiology, Benha University, National Heart Institute, Egypt
*Corresponding Author: Mohamed Abdelmonem Aboutaha, Department of Cardiology, Benha University, National Heart Institute, Egypt.
Received: August 11, 2020; Published: November 28, 2020




Abstract

Background: Identifying the transmural extent of myocardial necrosis and the degree of myocardial viability in acute myocardial infarction (AMI) is important clinically.

Aim of the Study: The aim of this study was to assess myocardial viability using two-dimensional speckle tracking imaging (2D-STI) in patients with AMI.

Methods: 2D-STI was performed within three days of hospital admission and six months after primary percutaneous coronary intervention (PCI) in 50 patients with AMI, who had a left anterior descending coronary artery (LAD) culprit lesion. In addition, 25 patients who had minimal stenotic lesions (< 30% stenosis) on coronary angiography were also included in the control group. At six months dobutamine echocardiography was performed for viability assessment in seven segments of the LAD territory. According to the recovery of wall motion abnormality, segments were classified as viable or non-viable.

Results: A total of 288 segments were viable, and 62 were nonviable. There is statistical significant difference between the viable and nonviable segments in the peak systolic strain and the peak systolic strain rate measured within three days from acute myocardial infarction. AUC for peak systolic strain (0.957, p. < 0.001), 95%C.I. (0.937 - 0.976) showed that a cut off level of < -9 had sensitivity of 86.11 and specificity 87.1 for prediction of viable myocardium. AUC for peak systolic strain rate (0.87, p. < 0.001), 95%C.I. (0.809 - 0.931) showed that a cut off level of < -0.7 had sensitivity of 91.6 and specificity 74.19 for prediction of viable myocardium.

Conclusion: In patients with recent first acute MI, Strain and strain rate measurements are feasible, inexpensive, quantitative, and rapid methods that can predict myocardial viability with high sensitivity and specificity.

Keywords: Acute Myocardial Infarction (AMI); Two-Dimensional Speckle Tracking Imaging (2D-STI); Percutaneous Coronary Intervention (PCI)

References

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Citation: Mohamed Abdelmonem Aboutaha., et al. “Early Prediction of Myocardial Viability Following Acute Myocardial Infarction by Two- Dimensional Speckle Imaging”. EC Cardiology 7.12 (2020): 34-45.

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