Research Article
Volume 8 Issue 2 - 2020
Malignant Arrhythmias and Sudden Death in Carriers of Non-Compacted Cardiomyopathy Determining by Non-Invasive Electrical Markers
Ana M Jerez Castro1*, Margarita Dorantes Sánchez2, Ailema A Alemán Fernández3, Yenia Escobar Ortega4, Rodrigo Aleaga Castro5 and Carlos Abdiel Casí Pita6
1Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba
2Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba
3Hospital de Vigo España
4Hospital Clínico Quirúrgico Docente Joaquín Albarrán
5Policlínico René Vallejo Ortiz
6nstituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba
*Corresponding Author: M Jerez Castro, Instituto de Cardiología y Cirugía Cardiovascular, La Habana, Cuba.
Received: October 29, 2020; Published: January 30, 2021




Abstract

Non-compacted ventricle cardiomyopathy characterized by spongiform morphology of the left ventricle, with ventricular trabeculations and intertrabecular spaces, secondary to arrest of the embryological compaction process.

Objective: To evaluate the behavior of arrhythmias through non-invasive electrical markers in carriers of non-compacted ventricular cardiomyopathy.

Methodological Design: An observational case-control and descriptive, cross-sectional study was conducted in 52 patients with non-compacted ventricular cardiomyopathy from the cases included between January 2006, December 2016, in a specialized consultation of the Institute of Cardiology, comparing them with the group selected from the same database, according to age, sex, race, of 65 patients with dilated cardiomyopathy of ischemic etiology and a control group (60). We explore: Personal pathological history, cardiovascular risk factors, echocardiography specifying the diagnostic criteria, non-invasive electrical markers: late potentials, prolongation and dispersion of QTc> 460 ms -∆QT> 65 ms, Tp –Te> 100msec and ∆Tp –Te > 30msec, T Wave variability, positivity of Holter arrhythmias, sudden death events.

Results: A mean age (42 ± 13.09), male sex, black and mixed race, alcoholism, smoking, prevailed, echocardiogram established diagnosis, positive late potentials 57 (87.6%) ischemic, upper 38 (73.0%) not compacted, Prolonged QTc 26 (50.0%) and dispersed in 38 (73.0%) not compacted, inferior (85.3%) ischemic dilated (85.3%), Tpeak-Tend prolongation and superior dispersion in ischemic, the T-wave widened in non-compacted and inverted in ischemic, documented arrhythmias in both groups, sudden death 9 (13.8%) ischemic, over 4 (7.69%) not compacted.

Conclusion: Non-invasive electrical markers, although positive in non-compacted ones, were more prevalent in ischemic dilatation, in correspondence with arrhythmias and sudden death events.

 

Keywords: Non-Compacted Cardiomyopathy; Non-Invasive Electrical Markers; Malignant Arrhythmias; Sudden Death

References

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Citation: Ana M Jerez Castro., et al. “Malignant Arrhythmias and Sudden Death in Carriers of Non-Compacted Cardiomyopathy Determining by Non-Invasive Electrical Markers”. EC Cardiology 8.2 (2021): 42-50.

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