Review Article
Volume 20 Issue 6 - 2021
Antibacterial Effect of Endodontic Irrigating Solutions in Pediatric Dentistry: A Systematic Review and Meta-Analysis
Nivedita Pande*, Amar Katre and Ashwin Jawdekar
Department of Pediatric and Preventive Dentistry, Y. M. T. Dental College and Hospital Under Maharashtra University of Health Sciences, India
*Corresponding Author: Nivedita Pande, Department of Pediatric and Preventive Dentistry, Y. M. T. Dental College and Hospital Under Maharashtra University of Health Sciences, India.
Received: April 22, 2021; Published: May 31, 2021




Abstract

Background: Removal of diseased pulpal tissue is paramount to the success of pulp therapy in primary teeth. Biomechanical canal preparation aids in removal of pulp along with shaping of the canal. However, owing to the tortuosity of the pulp canals in primary teeth, it may not possible to eliminate the pulp tissue or organic debris completely; hence the use of irrigants has been emphasised. A pulp canal space free of microbes is essential for obturation. Antibacterial efficacy of the endodontic irrigating solutions is hence deemed to be important. However, there is no clear consensus as to which irrigating solution in primary teeth has better antibacterial properties.

Objectives: To assess the antibacterial effectiveness of root canal irrigating solutions used in primary teeth using reduction in colony forming units as an outcome measure.

Search Methods: An electronic search was undertaken on PubMed, Embase, Scopus, Prospero and Google Scholar for articles on irrigating solutions used in pulpectomy in children. All electronic searches were last updated in August 2019. Search terms used were irrigating solutions, root canal irrigating solutions, antimicrobial, antibacterial and primary teeth.

Data Collection and Analysis: Two reviewers (N.P. and A.K.) independently extracted data using single Excel data extraction form from the study described. The data form continued the following information: author names and year of publication, study design, number of participants, age, type of intervention, change in colony forming units/ml in proportion and standardization of procedure.

Main Results: 4 trials (220 participants) were included. All four studies measured the outcome in terms of reduction in colony forming units (CFU/ml). The various agents used in the studies were N. Saline, Sodium Hypochlorite, MTAD and Morinda citrifolia. The pooled OR showed no statistical difference between the antibacterial efficacy of any of the irrigating solutions (OR 0.45 (0.10 - 1.96)). There was a moderate heterogeneity (p = 0.03, I2 = 66%). The overall risk of bias was unclear.

Conclusion: All irrigating solutions have antibacterial properties when used in primary teeth; however there is inconclusive evidence regarding the superiority of any one over the other. Evidence available for assessing the effectiveness of antibacterial properties of various root canal irrigating solutions used in primary teeth is of poor quality.

 

Keywords: Antibacterial Effectiveness; Primary Teeth; Root Canal Irrigating Solutions; Pulpectomy

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Citation: Nivedita Pande., et al. “Antibacterial Effect of Endodontic Irrigating Solutions in Pediatric Dentistry: A Systematic Review and Meta-Analysis”. EC Dental Science 20.6 (2021): 68-81.

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