Review Article
Volume 20 Issue 7 - 2021
Peppermint (Mentha piperita L.) Essential Oil in Systemic and Oral Health
R E Carlson1, R M Buch2 and JA von Fraunhofer3*
1Executive Director, Research and Analytical Sciences, D. Gary Young Research Institute, Lehi, UT, USA
2Formerly, Chief Scientific Officer, Young Living, Lehi, UT, USA
3Professor Emeritus, University of Maryland, Baltimore, MD, USA
*Corresponding Author: JA von Fraunhofer, Professor Emeritus, University of Maryland, Baltimore, MD, USA.
Received: May 13, 2021; Published: June 25, 2021


Peppermint has been used since antiquity as a flavorant, but the oil also has been used for thousands of years to treat a variety of systemic health and skin conditions. Although the chemical make-up is complex, the primary components of the oil are the monoterpenes menthol and menthone together with various other terpenes.

The traditional medicinal use of peppermint oil has been to treat digestive disorders, especially irritable bowel syndrome (IBS) and as an anti-spasmodic, the latter being due to the effect of menthol on 5-HT3 receptors. The ability of peppermint to disrupt biofilms and its antifungal activity has stimulated its use in dentistry and oral care.

Various clinical studies indicate that peppermint can markedly benefit participation in sports and athletic activities, inducing enhanced strength and performance.

There are indications that ingested peppermint oil can interact with certain prescription medications that are metabolized by the hepatic system, these include cyclosporin and Cytochrome P450 1A2 as well as some anti-depressants, the anti-psychotic drug haloperidol, anti-nausea drugs, the beta-blocker propranolol and hypertensives and angina drugs. There do not appear to be any problems of interactions with medications associated with drinking mint tea or with topical use of peppermint oil.

Keywords: Irritable Bowel Syndrome (IBS); Peppermint Oil; Mint Tea


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Citation: JA von Fraunhofer., et al. “Peppermint (Mentha piperita L.) Essential Oil in Systemic and Oral Health”. EC Dental Science 20.7 (2021): 43-55.

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