Research Article
Volume 20 Issue 8 - 2021
Efficacy of i-PRF as a Local Drug Delivery with Scaling and Root Planing in the treatment of Chronic Periodontitis
Hanku Ramavath1, Juliet Josephin2, Rajababu Palaparthy3, Mounika Basavaraju4, Abhinav Atchuta5 and Suryakanth Malgikar5*
1Senior Resident, Department of Periodontology, Government Dental College and Hospital, Hyderabad, Telangana, India
2Department of Periodontology, Reader, Kamineni Institute of Dental Sciences, Narketpally, Telangana, India
3Professor, Department of Periodontology, Kamineni Institute of Dental Sciences, Narketpally, Telangana, India
4Senior Lecturer, Department of Periodontology, Kamineni Institute of Dental Sciences, Narketpally, Telangana, India
5Reader, Department of Periodontology, Kamineni Institute of Dental Sciences, Narketpally, Telangana, India
*Corresponding Author: Suryakanth Malgikar, Reader, Department of Periodontology, Kamineni Institute of Dental Sciences, Narketpally, Telangana, India.
Received: May 25, 2021; Published: July 29, 2021




Abstract

Aim: The present study was planned to evaluate clinically the efficacy of i-Platelet Rich Fibrin injected locally into the periodontal pocket.

Materials and Methods: A total of 30 sites with pocket depths 5 - 6 mm were chosen as a split mouth design. Selected sites were randomly divided into two groups to receive scaling and root planing with injectable Platelet Rich Fibrin (SRP+i-PRF) (Test) and scaling and root planing (SRP) alone (Control). Clinical parameters like modified sulcular bleeding index (mSBI) and probing pocket depth (PPD) was recorded at baseline and 3 months interval.

Results: A significant reduction in mSBI, probing pocket depth (PPD), was observed from base line to 3 months in both the groups. However, results were found to be statistically significant in the SRP+i-PRF group (test).

Conclusion: SRP+i-PRF group showed positive results, however further studies are needed to evaluate i-PRF as a local drug delivery.

Clinical Significance: There is currently widespread interest for the use of various biomaterials to locally deliver biomolecules for regeneration. This article focuses on the use of liquid version of platelet rich fibrin as a local drug delivery for the fast delivery of growth factors.

Keywords: Chronic Periodontitis; i-PRF; Local Drug Delivery; Scaling and Root Planing

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Citation: Suryakanth Malgikar., et al. “Efficacy of i-PRF as a Local Drug Delivery with Scaling and Root Planing in the treatment of Chronic Periodontitis”. EC Dental Science 20.8 (2021): 39-50.

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