Research Article
Volume 20 Issue 10 - 2021
Dental Care Awareness of Oral Complications among Patients Receiving Denosumab and Zoledronic Acid Therapy at KAMC Oncology Department
Malaz Mandourah1*, Jumanah Bahatheq1, Weaam Kaki1 and Rajaa Matahen2
1Faculty of Dentistry, Umm Alqura University, Makkah, Saudi Arabia
2Division of Cardiac Clinical Pharmacology, King Abdullah Medical City, Makkah, Saudi Arabia
*Corresponding Author: Malaz Mandourah, Faculty of Dentistry, Umm Alqura University, Makkah, Saudi Arabia.
Received: September 06, 2021; Published: September 25, 2021


Background: Many risk factors for developing medication-related osteonecrosis of the jaw (MRONJ) have been reported in the literature, and patients’ awareness is an important factor for developing MRONJ. We aim to evaluate patients' awareness about oral complications regarding these drugs. We also aim to assess the frequency of complications and the attitudes to these complications.

Methods: A cross-sectional questionnaire-based study was conducted at King Abdullah Medical City in Saudi Arabia to assess the relevant outcomes, after obtaining ethical approval from the included patients.

Results: We have finally included 183 participants, including 23 (12.6%) males, and 160 (87.4%) females. Five patients (2.7%) were in the 15 - 35 years old group, while the rest (97.3%) were > 35 years old. Most patients (97.3%) were familiar with drugs through doctors, and 153 patients (83.6%) used the prescribed drugs for more than 3 months. Pain in teeth/jaw (28.45), dry mouth (27.3%), and gingival sensitivity (19.7%) were the commonest oral manifestations. Besides, 73.8% did not know about the side effects of the drugs, while only 46 (25.1%) were aware of the oral complications of the drugs. Age, gender, and the frequency of brushing teeth might significantly impact some important awareness domains.

Conclusion: Our results indicate the low awareness levels among our population, indicating the need to apply proper interventional approaches and educational campaigns.

Keywords: Dental Care; Awareness; Oral Complications; Denosumab; Zoledronic Acid Therapy


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Citation: Malaz Mandourah., et al. “Dental Care Awareness of Oral Complications among Patients Receiving Denosumab and Zoledronic Acid Therapy at KAMC Oncology Department”. EC Dental Science 20.10 (2021): 95-106.

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