Research Article
Volume 4 Issue 6 - 2020
Oral Glucose Tolerance Tests (OGTT) with Alpinia malaccensis Aerial Parts and Rhizome Extracts
Rashed Reza, M M Sultan Mahmud, Md Sohrab Hosen and Mohammed Rahmatullah*
Department of Pharmacy, University of Development Alternative, Lalmatia, Dhaka, Bangladesh
*Corresponding Author: Mohammed Rahmatullah, Professor, Dean, Faculty of Life Sciences, University of Development Alternative, Lalmatia, Dhaka, Bangladesh..
Received:May 11, 2020; Published: May 27, 2020




Abstract

Diabetes is a metabolic disorder affecting glucose metabolism and homeostasis within the body. In recent years, diabetes has been affecting both young and old, and the number of diabetic and pre-diabetic people have risen to alarming proportions throughout the world. The disease, characterized by high blood glucose levels, rapidly leads to other serious disorders affecting the eyes, kidneys, heart, and brain. Allopathic and traditional medicines can treat only the symptoms but cannot totally cure the disease. Scientists have focused their attention on the plant kingdom in efforts to discover better and more affordable allopathic drugs. Oral glucose tolerance test (OGTT) is one of the ways in which the anti-hyperglycemic efficacy of a drug or formulation can be tested rapidly. We report here that in OGTT, methanol extract of both aerial parts and rhizomes of a Zingiberaceae family plant, Alpinia malaccensis showed promising anti-hyperglycemic efficacy comparable to that of a standard drug, glibenclamide. 

Keywords: Diabetes Mellitus; Alpinia malaccensis; Zingiberaceae; OGTT

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Citation: Mohammed Rahmatullah., et al. “Oral Glucose Tolerance Tests (OGTT) with Alpinia malaccensis Aerial Parts and Rhizome Extracts". EC Nutrition 4.6 (2020): 15-20.

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