Research Article
Volume 5 Issue 4 - 2021
Risk Factors Associated with Long-Term Hospitalization COVID-19 Patients in Hadhramout, Yemen 2020
Shouqi Abdullah Al-Akabari1, Maryam Hamed Baras2*, Eidha Ali Bin-Hameed3 and Tahani Aidroos Al-Afifi4
1Department of Diagnostic Medicine, Ministry of Public Health and Population and Molecular Biology Diagnostic Unit, Ministry of Public Health and Population, Hadhramout Coast, Yemen
2Biology Department, Faculty of Science, Hadhramout University and Molecular Biology Diagnostic Unit, Ministry of Public Health and Population, Hadhramout Coast, Yemen
3Biology Department, Faculty of Science, Hadhramout University and Health Science Department, Faculty of Medicine and Health Sciences, University of Science and Technology, Hadhramout, Yemen
4National Center for Public Health Laboratories - Hadhramout Branch, Ministry of Public Health and Population and Molecular Biology Diagnostic Unit, Ministry of Public Health and Population, Hadhramout coast, Yemen
*Corresponding Author: Maryam Hamed Baras, Biology Department, Faculty of Science, Hadhramout University and Molecular Biology Diagnostic Unit, Ministry of Public Health and Population, Hadhramout Coast, Yemen.
Received: February 26, 2021; Published: March 23, 2021




Abstract

Objective: The different hospitalization durations of COVID-19 patients must be studied to understand the risk factors associated with long-term hospitalization. So, the clinical features may help to identify these potential risk factors.

Methodology: In this retrospective study. 60 patients who were symptomatic presentations of COVID-19 were included. We determined and evaluated the risk factors associated with long-term hospitalization COVID-19 patients during 7th April and 29th August 2020.

Results: In this retrospective study we enrolled 60 COVID-19 repeat cases visited corona isolation centers of Ibn sinna hospital and Dr. Rijad hospital. 30 (50%) were positive repeat cases and 30 (50%) were negative repeat cases. Age more than 60 years was significant independent risk factor for long-term hospitalization (P value = 0.008). However, the other studied risk factors like gender, fever, cough, sore throat, Pneumonia, shortness of breath, Rhinorrhea, Myalgia and comorbidities disease hadn't significant association. A multivariate regression analysis showed that COVID-19 patients which their ages more than 60 years are more likely to have long-term hospitalization by 1.458 than the other patients equal or less than 60 years.

Conclusion: In long-term hospitalization COVID-19 patients, age groups were the only significant independent risk factor with long-term hospitalization group in our study.

Recommendations: Older COVID-19 patients should have had as special care and monitoring because they are the most likely to have any progression in their cases leading to stay long duration in hospitals by 1.458 than younger patients.

Keywords: COVID-19; Infection; Long-Term Hospitalization; Risk Factors; SARS-CoV-2

References

  1. Petrosillo N., et al. "COVID-19, SARS and MERS: are they closely related?". Clinical Microbiology and Infection 26 (2020): 729-734.
  2. Unhale SS., et al. "A Review On Corona Virus (COVID-19)". International Journal of Pharmaceutical and Life Sciences 4 (2020): 109-115.
  3. Dhama K., et al. "Coronavirus Disease 2019 – COVID-19". Preprint (2020).
  4. Abdur Rahman., et al. "Risk Factors of the Severity of COVID-19: a Meta-Analysis. Preprint (2020).
  5. Hafeez A., et al. "A Review of COVID-19 (Coronavirus Disease-2019) Diagnosis, Treatments and Prevention". EJMO2 (2020): 116-125.
  6. Lippi G., et al. "Current laboratory diagnostics of coronavirus disease 2019 (COVID-19)". Acta Biomed 2 (2020): 137-145.
  7. Qiao X., et al. "Re-positive Cases of Nucleic Acid Tests in Discharged Patients With COVID-19: A Follow-Up Study". Frontiers in Medicine349 (2020): 1-8.
  8. Petrilli CM., et al. "Factors associated with hospitalization and critical illness among 4,103 patients with Covid-19 disease in New York City". BMJ 369 (2020): m1966.
  9. Jameel T., et al. "Persistence of Reverse Transcription- Polymerase Chain Reaction (RT-PCR) Positivity in COVID-19 Recovered Patients: A Call for Revised Hospital Discharge Criteria". Cureus7 (2020): e9048.
  10. Xu K., et al. "Factors Associated With Prolonged Viral RNA Shedding in Patients with Coronavirus Disease 2019 (COVID-19)". Clinical Infectious Diseases 71 (2020a): 799-806.
  11. Xu L., et al. "Risk factors for severe corona virus disease 2019 (COVID-19) patients: a systematic review and meta-analysis". Med Rxiv (2020b).
  12. Guan W., et al. "Clinical Characteristics of Coronavirus Disease 2019 in China". The new England Journal of Medicine (2020): 1-13.
  13. Zhao W., et al. "Clinical characteristics and durations of hospitalized patients with COVID-19 in Beijing: a retrospective cohort study". medRxiv (2020).
  14. Wu Y., et al. "Risk Factors Associated With Long-Term Hospitalization in Patients With COVID-19: A Single-Centered, Retrospective Study". Frontiers in Medicine315 (2020): 1-10.
  15. Chang M., et al. "Risk factors for disease progression inCOVID-19 patients". BMC Infectious Diseases445 (2020): 2-6.
  16. Liu W., et al. "Analysis of factors associated with disease outcomes in hospitalized patients with 2019 novel coronavirus disease". Chinese Medical Journal9 (2020): 1032-1038.
  17. Garg S., et al. "Hospitalization Rates and Characteristics of Patients Hospitalized with Laboratory-Confirmed Coronavirus Disease 2019 - COVID-NET, 14 States, March 1–30, 2020". Morbidity and Mortality Weekly Report15 (2020): 458-464.
  18. Thai P., et al. "Factors associated with the duration of hospitalisation among COVID-19 patients in Vietnam: A survival analysis". Epidemiology and Infection 148 (2020): e114.
  19. Cen Y., et al. "Risk factors for disease progression in patients with mild to moderate coronavirus disease 2019da multi-centre observational study". Clinical Microbiology and Infection2020 (2020): 1242-1247.
  20. Mo P., et al. "Risk factors for delayed negative conversion of SARS-CoV-2 in patients with COVID-19 pneumonia: a retrospective cohort study". Epidemiology and Infection 148 (2020): e293.
  21. Shen L., et al. “Clinical and laboratory-derived parameters of 119 hospitalized patients with coronavirus disease 2019 in Xiangyang, Hubei Province, China". Journal of Infection2020 (2020): 147-178.
  22. Kaeuffer C., et al. "Clinical characteristics and risk factors associated with severe COVID-19: prospective analysis of 1,045 hospitalised cases in North-Eastern France, March 2020". Euro Surveill (2020): 1-10.
  23. Zhang J., et al. "Risk factors for disease severity, unimprovement, and mortality in COVID-19 patients in Wuhan, China". Clinical Microbiology and Infection 26 (2020): 767-772.
Citation: Maryam Hamed Baras., et al. “Risk Factors Associated with Long-Term Hospitalization COVID-19 Patients in Hadhramout, Yemen 2020”. EC Emergency Medicine and Critical Care 5.4 (2021): 64-70.

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