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Review Article
Volume 5 Issue 11 - 2020
The Application of Fullerene Derivatives in Medicine and Specific Endocrinological Conditions
Nicholas A Kerna1*, John V Flores2,3 and Kevin D Pruitt4, Uzoamaka Nwokorie5 and Hilary M Holets2,3
1SMC–Medical Research, Thailand
2Beverly Hills Wellness Surgical Institute, USA
3Orange Partners Surgicenter, USA
4Kemet Medical Consultants, USA
4University of Washington, USA
*Corresponding Author: Nicholas A Kerna, POB47 Phatphong, Suriwongse Road, Bangkok, Thailand 10500.
Received: September 15, 2020; Published: October 29, 2020


Fullerene derivatives have select properties that have attracted investigation regarding applications in medicine. For the most part, they have demonstrated high biocompatibility and low toxicity in humans and animals. They have shown antimicrobial, antiviral, and antioxidant properties, and act as an ROS-scavenger. Specific fullerene derivatives are being considered in treating multiple sclerosis, skin disorders, HIV infection, cancer, ischemia, and osteoporosis. They have shown a potential for applications in dermatology, treating acne vulgaris and erythema. Specific fullerene derivatives are used as a synergistic agent in diagnostic imaging, biosensing, drug-delivery, targeted therapy, and theranostic procedures. Exposure to certain fullerene materials can be hazardous to human health, particularly as potential endocrine disruptors. Nevertheless, fullerene derivatives are showing promise in their adjunctive application in medicine and specific endocrinological disorders.

Keywords: Antioxidant; Biocompatibility; Biosensing; Diagnostic Imaging; Drug-Delivery; Endocrinological Disorders; Fullerene


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Citation: Kerna NA, Flores JV, Pruitt KD, Nwokorie U, Holets H. The Application of Fullerene Derivatives in Medicine and Specific Endocrinological Conditions. EC Endocrinology and Metabolic Research. 2020 Sep 15; 5.11: 56-66.

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