Case Report
Volume 7 Issue 3 - 2020
Hereditary Angioedema: An Unusual Cause of Abdominal Pain
Sara Ghani*, Nadia Benzzoubeir, Laaziza Chahed Ouazzani and Ikram Errabih
Hepato-Gastroenterology and Proctology, ‘Medicine B’ Department, Ibn Sina Hospital, Mohammed V University-FMPR, Rabat, Morocco
*Corresponding Author: Sara Ghani, Hepato-Gastroenterology and Proctology, ‘Medicine B’ Department, Ibn Sina Hospital, Mohammed V University-FMPR, Rabat, Morocco.
Received: February 06, 2020; Published: February 14, 2020




Abstract

Introduction: Hereditary angioedema (HAE) is a genetic disease that affects about one in 50,000 people. It’s characterized by recurrent episodes of edema and associated with a deficiency of C1-inhibitor.

Case Report: We report a very rare case of hereditary angioedema, presenting as recurrent abdominal pain. A 37-year-old patient consults for recurrent abdominal pain, chronic vomiting and edema of the face and hands. Those symptoms started in childhood and disappear in a few days. Abdominal ultrasounds and CT scans are normal. All upper endoscopies performed were normal. The C4 complement level and the concentration of C1 esterase inhibitor were low. HAE type I was retained and the patient started tranexamic acid substitution with a resolution of symptoms.

Conclusion: The clinician should think about hereditary angioedema when other causes of recurrent abdominal pain are ruled out, especially in patients with a history of recurrent episodes of edema and proceed to the investigation of C3 and C4 levels then of C1 esterase inhibitor if levels of C4 are low.

Keywords: Hereditary Angioedema; Abdominal Pain; C4 Complement; Prophylaxis

Citation: Sara Ghani., et al. “Hereditary Angioedema: An Unusual Cause of Abdominal Pain”. EC Gastroenterology and Digestive System 7.3 (2020): 01-03.

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