Mini Review
Volume 7 Issue 6 - 2020
Gastrointestinal and Hepatobiliary Manifestations of SARS-CoV-2 Virus in COVID-19 Patients
Ghady Moafa and Nyan L Latt2,3*
1Department of Internal Medicine, Ochsner Medical Center, USA
2Division of Gastroenterology, Ochsner Health/Ochsner Clinical School, University of Queensland, USA
3Ochsner Multi-organ Transplant Institute, Ochsner Health, Clinical Assistant Professor of Medicine, Louisiana State University, New Orleans, Senior Lecturer, Ochsner Clinical School, University of Queensland, USA
*Corresponding Author: Nyan L Latt, Transplant Hepatology, Ochsner Multi-Organ Transplant Institute, Ochsner Health System, Senior Lecturer and GI Clerkship Director, Ochsner Clinical School, The University of Queensland, Clinical Assistant Professor of Medicine, Louisiana State University, New Orleans, USA.
Received: April 26, 2020; Published: May 11, 2020


COVID-19 disease is an ongoing severe respiratory viral disease that emerged in December 2019. COVID-19 is caused by a novel coronavirus, first isolated in January 2020, known as SARS-CoV-2. COVID-19 has been declared as a global pandemic by the World Health Organization as it has already spread across the continents. SARS-CoV-2 virus enters the cells via the ACE-2 receptor. The ACE-2 receptor is highly expressed in the lungs in addition to other organs in the gastrointestinal tract, such as the esophagus, small and large intestines, ileum, colon and cholangiocytes. Although COVID-19 frequently present with fever, body aches, respiratory symptoms such as cough, shortness of breath, it can rarely present with gastrointestinal symptoms. Diarrhea is the most common gastrointestinal manifestation; however, nausea, vomiting and abdominal pain have been reported. Acute liver injury and pancreatic injury are not uncommon in patients with severe COVID-19. It is, therefore, vital for the clinicians to recognize gastrointestinal and hepatobiliary manifestations in patients suspected with COVID-19 and conduct early diagnostic workup.

Keywords: SARS-CoV-2; COVID-19; Pandemic; Symptoms of COVID-19; Gastrointestinal manifestations of COVID-19; Liver Injury in COVID-19; Novel Corona Virus; Diarrhea in COVID-19; Pancreatitis in COVID-19


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Citation: Ghady Moafa and Nyan L Latt. “Gastrointestinal and Hepatobiliary Manifestations of SARS-CoV-2 Virus in COVID-19 Patients”. EC Gastroenterology and Digestive System 7.6 (2020): 28-32.

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