Research Article
Volume 7 Issue 8 - 2020
New Options in Management of Iron-Deficiency Syndromes in Inflammatory Bowel Diseases
NI Stuklov1,2*, IG Basiladze1,3, MS Kovalchuk1, AV Pivnik1,3, OV Knyazvev3, AI Parfenov3 and G Tarantino4
1Peoples’ Friendship University of Russia (RUDN University), Moscow, Russia
2National Medical Research Radiological Center, Moscow, Russia
3Loginov Moscow Clinical Scientific Center, Moscow, Russia
4Pharmanutra Spa, Scientific Department, Pisa, Italy
*Corresponding Author: NI Stuklov, Peoples’ Friendship University of Russia (RUDN University), Moscow, Russia.
Received: May 15,2020; Published: July 17, 2020


The article describes the most common iron deficiency syndromes (IDS) in inflammatory bowel disease (IBD) and presents the modern principles of differential diagnosis of gastrointestinal disease, the advantages and disadvantages of standard methods for the correction of iron-deficiency (ID) and anemia in this group of patients.

The authors give a circumstantial outline of their own data regarding the examination and treatment of 77 patients with IBD and anemia and prove the necessity of compulsory serum ferritin (SF) testing as the most important differential marker of the IDs. Inadequate production of erythropoietin as the main cause of anemia was observed in 15% of patients with high SF values. On the contrary, the necessity of mandatory use of iron preparations in management of anemia was determined in 85% of patients. The high effectiveness and safety of Sucrosomial® iron were proved in patients with IBD and anemia.

The effectiveness of this method showed the normalization of hemoglobin in 68% of patients within 3 months. In contrast, intravenous iron administered during the inpatient treatment period was not sufficiently effective in this category of patients, which required the continuation of outpatient therapy with preparations of Sucrosomial® iron.

Based on the obtained data and international experience, there was formulated and substantiated the algorithm of differentiated therapy of IDS in patients with a mild form of IBD.

Keywords: Iron Deficiency; Iron Deficiency Syndrome; Inflammatory Bowel Disease; Treatment of Anemia; Sucrosomial® Iron; Intravenous Iron


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Citation: NI Stuklov., et al. “New Options in Management of Iron-Deficiency Syndromes in Inflammatory Bowel Diseases”. EC Gastroenterology and Digestive System 7.8 (2020): 94-104.

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