Case Series
Volume 8 Issue 4 - 2021
Upper Gastrointestinal Tract Schwannomas- Report of Three Cases and Literature Review
Kamran Mushtaq*, Manik Sharma, Muhammad ElBadri, Arsalan Ahmad and Saad Al Kaabi
Department of Gastroenterology, Hamad General Hospital, Doha, Qatar
*Corresponding Author: Kamran Mushtaq, Department of Gastroenterology, Hamad Medical Corporation, Doha, Qatar.
Received: March 23, 20211; Published: April 15, 2021


Background: Schwannoma is a benign mesenchymal tumor arising from peripheral nerve sheath. Schwannoma can occur sporadically or as a part of hereditary syndromes like Neurofibromatosis. Schwannomas are rare tumors in the gastrointestinal tract, the stomach being the most common site. Esophageal Schwannoma is even rarer, with fewer than 90 cases reported.

Methods: We report 3 cases of upper GI schwannomas (Gastric-2 Esophageal-1). The average age of detection was 36 years, and two of them were males. The average size of the tumor at detection was about 2.5 cm. Two of them required laparoscopic resection, and one of them was treated endoscopically. Histopathology revealed strong S-100 positivity on immunohistochemistry, and all of them were of benign nature.

Conclusion: Schwannomas are clinically, endoscopically and radiologically difficult to distinguish from gastrointestinal stromal tumors (GIST). Distinguishing Schwannoma from GIST is important as the latter has malignant potential. Schwannomas have a good prognosis with an extremely low recurrence rate.


Keywords: Gastric Schwannoma; Esophageal Schwannoma; GIST; Submucosal Tumors; Endoscopic Ultrasound


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Citation: Kamran Mushtaq., et al. “Upper Gastrointestinal Tract Schwannomas- Report of Three Cases and Literature Review”. EC Gastroenterology and Digestive System 8.4 (2021): 22-29.

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