Research Article
Volume 8 Issue 6 - 2021
Combined Staged Treatment of Villous Tumours of the Rectum and Colon
VL Denisenko1*, SP Bukhtarevich1, Yu M Gain2 and VA Pryshchepenka3
1Department of Health “Vitebsk Regional Specialized Clinical Center”, Vitebsk, Republic of Belarus
2State Educational Institution “Belarusian Medical Academy of Postgraduate Education”, Minsk, Republic of Belarus
3State Educational Institution “Vitebsk State Order of Peoples’ Friendship Medical University”, Vitebsk, Republic of Belarus
*Corresponding Author: VL Denisenko, Department of Health “Vitebsk Regional Specialized Clinical Center”, Vitebsk, Republic of Belarus.
Received: March 17, 2021; Published: May 17, 2021




Abstract

Aim of the Study: To develop and introduce into clinical practice a method of staged treatment of villous tumors of the colon based on using the combination of diathermocoagulation and high-intensity laser radiation.

Materials and Methods: The patients were divided into 2 groups. The first (control) group included 80 patients and were treated only with using of endoscopic loop and electricity energy. The second (examined) group consisted of 52 patients. Their treatment included combination of two methods: endoscopic excision with an endoscopic loop and laser vaporization of the tumor base. The patients of both control and examined groups had villous tumors with size from 1.5 to 8 - 9 cm in diameter. In some cases, the base of the tumor occupied up to half of the intestinal lumen, the length reached 8 - 9 cm. Depending on the size of the tumor removal was performed in one stage or in several steps (multistage). In 32 cases tumors excision were performed by its fragmentation during one procedure, in 20 cases the tumors were removed in several stages.

Results. In the control group of patients, tumors up to 2 - 3 cm in diameter in most cases were removed during one procedure. The lesions larger than 3 cm were removed during one or more procedures at the first hospitalization. The relapse rate in this group was 30%. Laser vaporization was used in patients of the examined group. The method was used to vaporize the base of the tumor after endoscopic electroresection of its exophytic part. Relapse of the disease in the second group was observed in 5% of patients.

Conclusion: The use of diathermocoagulation (loop excision of the tumor) and high-intensity laser radiation of various wavelengths can reduce the relapse rate of the disease from 30 to 5%, making this intervention the operation of choice in the treatment of large villous adenomas of the colon.

 

Keywords: Villous Tumor; Loop Excision; Laser Vaporization; Staged Treatment

References

  1. Uryadov SE. “Diagnostic and therapeutic endoscopy for surgical diseases of the colon”. Sovremennie problemi Nauki i Obrazovaniya (Electronic Journal) 2 (2012).
  2. Huber AR and Shikle JF. “Benign fibroblastic polyps of the colon”. Archives of Pathology and Laboratory Medicine 11 (2009): 1872-1878.
  3. Chaparro M., et al. “Accuracy of computed tomographic colonography for the detection of polyps and colorectal tumors: a systematic review and meta-analysis”. Digestion1 (2009): 1-17.
  4. Kovács M., et al. “Screening and surveillance for hereditary polyposis and non-polyposis syndromes with capsule endoscopy”. Orvosi Hetilap 14 (2008): 639-644.
  5. Menardo G. “Sensitivity of diagnostic examinations for colorectal polyps”. Techniques in Coloproctology2 (2004): 273-275.
  6. Lapteva EA., et al. “Colon polyps: epidemiology, risk factors, diagnostic criteria and courses of treatment (review)”. Saratov Journal of Medical Scientific Research2 (2013): 252-259.
  7. Groen P., et al. “Long-term colorectal-cancer mortality after adenoma removal”. New England Journal of Medicine 21 (2014): 2035-2037.
  8. Repici A and Tricerri R. “Endoscopic polypectomy: techniques, complications and follow-up”. Techniques in Coloproctology 2 (2004): 283-290.
  9. Iida Y., et al. “Endoscopic resection of large colorectal polyps using a clipping method”. Diseases of the Colon and Rectum 2 (1994): 179-180.
  10. Zalit N YU., et al. “Morbidity and primary multiplicity of colon cancer”. Klinicheskaya Meditsina 2 (2006): 15-19.
  11. Aleksandrov VB. “Rectal cancer”. Moscow: Vuzovskaya kniga (2006).
  12. Denisenko VL. “The first experience of the use of transanal endoscopic microsurgery in the treatment of a tumor of the rectum”. Novosti Hirurgii19 (2011): 128-131.
Citation: VL Denisenko., et al. “Combined Staged Treatment of Villous Tumours of the Rectum and Colon”. EC Gastroenterology and Digestive System 8.6 (2021): 08-14.

PubMed Indexed Article


EC Pharmacology and Toxicology
LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.

PMID: 31143884 [PubMed]

PMCID: PMC6536005


EC Pharmacology and Toxicology
Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.

PMID: 31565701 [PubMed]

PMCID: PMC6764777


EC Neurology
Differences in Rate of Cognitive Decline and Caregiver Burden between Alzheimer's Disease and Vascular Dementia: a Retrospective Study.

PMID: 27747317 [PubMed]

PMCID: PMC5065347


EC Pharmacology and Toxicology
Will Blockchain Technology Transform Healthcare and Biomedical Sciences?

PMID: 31460519 [PubMed]

PMCID: PMC6711478


EC Pharmacology and Toxicology
Is it a Prime Time for AI-powered Virtual Drug Screening?

PMID: 30215059 [PubMed]

PMCID: PMC6133253


EC Psychology and Psychiatry
Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.

PMID: 30417173 [PubMed]

PMCID: PMC6226033


EC Anaesthesia
Arrest Under Anesthesia - What was the Culprit? A Case Report.

PMID: 30264037 [PubMed]

PMCID: PMC6155992


EC Orthopaedics
Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.

PMID: 30198026 [PubMed]

PMCID: PMC6124505


EC Pulmonology and Respiratory Medicine
Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012.

PMID: 30294723 [PubMed]

PMCID: PMC6169793


EC Dental Science
Important Dental Fiber-Reinforced Composite Molding Compound Breakthroughs

PMID: 29285526 [PubMed]

PMCID: PMC5743211


EC Microbiology
Prevalence of Intestinal Parasites Among HIV Infected and HIV Uninfected Patients Treated at the 1o De Maio Health Centre in Maputo, Mozambique

PMID: 29911204 [PubMed]

PMCID: PMC5999047


EC Microbiology
Macrophages and the Viral Dissemination Super Highway

PMID: 26949751 [PubMed]

PMCID: PMC4774560


EC Microbiology
The Microbiome, Antibiotics, and Health of the Pediatric Population.

PMID: 27390782 [PubMed]

PMCID: PMC4933318


EC Microbiology
Reactive Oxygen Species in HIV Infection

PMID: 28580453 [PubMed]

PMCID: PMC5450819


EC Microbiology
A Review of the CD4 T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population

PMID: 26280024 [PubMed]

PMCID: PMC4533840


EC Neurology
Identifying Key Symptoms Differentiating Myalgic Encephalomyelitis and Chronic Fatigue Syndrome from Multiple Sclerosis

PMID: 28066845 [PubMed]

PMCID: PMC5214344


EC Pharmacology and Toxicology
Paradigm Shift is the Normal State of Pharmacology

PMID: 28936490 [PubMed]

PMCID: PMC5604476


EC Neurology
Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia

PMID: 28713879 [PubMed]

PMCID: PMC5510658


EC Neurology
Unilateral Frontosphenoid Craniosynostosis: Case Report and a Review of the Literature

PMID: 28133641 [PubMed]

PMCID: PMC5267489


EC Ophthalmology
OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling

PMID: 29333536 [PubMed]

PMCID: PMC5766278


EC Neurology
Longer Duration of Downslope Treadmill Walking Induces Depression of H-Reflexes Measured during Standing and Walking.

PMID: 31032493 [PubMed]

PMCID: PMC6483108


EC Microbiology
Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.

PMID: 30957099 [PubMed]

PMCID: PMC6448571


EC Nutrition
Food Insecurity among Households with and without Podoconiosis in East and West Gojjam, Ethiopia.

PMID: 30101228 [PubMed]

PMCID: PMC6086333


EC Ophthalmology
REVIEW. +2 to +3 D. Reading Glasses to Prevent Myopia.

PMID: 31080964 [PubMed]

PMCID: PMC6508883


EC Gynaecology
Biomechanical Mapping of the Female Pelvic Floor: Uterine Prolapse Versus Normal Conditions.

PMID: 31093608 [PubMed]

PMCID: PMC6513001


EC Dental Science
Fiber-Reinforced Composites: A Breakthrough in Practical Clinical Applications with Advanced Wear Resistance for Dental Materials.

PMID: 31552397 [PubMed]

PMCID: PMC6758937


EC Microbiology
Neurocysticercosis in Child Bearing Women: An Overlooked Condition in Mozambique and a Potentially Missed Diagnosis in Women Presenting with Eclampsia.

PMID: 31681909 [PubMed]

PMCID: PMC6824723


EC Microbiology
Molecular Detection of Leptospira spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.

PMID: 31681910 [PubMed]

PMCID: PMC6824726


EC Neurology
Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases.

PMID: 31528859 [PubMed]

PMCID: PMC6746603


EC Psychology and Psychiatry
Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?

PMID: 31276119 [PubMed]

PMCID: PMC6604646


EC Anaesthesia
Real Time Locating Systems and sustainability of Perioperative Efficiency of Anesthesiologists.

PMID: 31406965 [PubMed]

PMCID: PMC6690616


EC Pharmacology and Toxicology
A Pilot STEM Curriculum Designed to Teach High School Students Concepts in Biochemical Engineering and Pharmacology.

PMID: 31517314 [PubMed]

PMCID: PMC6741290


EC Pharmacology and Toxicology
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese.

PMID: 31633124 [PubMed]

PMCID: PMC6800226


EC Neurology
Research Volunteers' Attitudes Toward Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.

PMID: 29662969 [PubMed]

PMCID: PMC5898812


EC Pharmacology and Toxicology
Hyperbaric Oxygen Therapy for Alzheimer's Disease.

PMID: 30215058 [PubMed]

PMCID: PMC6133268


News and Events


July Issue Release

We always feel pleasure to share our updates with you all. Here, notifying you that we have successfully released the July issue of respective journals and the latest articles can be viewed on the current issue pages.

Submission Deadline for Upcoming Issue

ECronicon delightfully welcomes all the authors around the globe for effective collaboration with an article submission for the upcoming issue of respective journals. Submissions are accepted on/before July 18, 2022.

Certificate of Publication

ECronicon honors with a "Publication Certificate" to the corresponding author by including the names of co-authors as a token of appreciation for publishing the work with our respective journals.

Best Article of the Issue

Editors of respective journals will always be very much interested in electing one Best Article after each issue release. The authors of the selected article will be honored with a "Best Article of the Issue" certificate.

Certifying for Review

ECronicon certifies the Editors for their first review done towards the assigned article of the respective journals.

Latest Articles

The latest articles will be updated immediately on the articles in press page of the respective journals.