Research Article
Volume 8 Issue 11 - 2021
Possibilities of Using Placenta Hydrolysate in Patients with COVID-19
Sayfutdinov RR1,2, Maksimov VA3, Khasanov R Sh1, Akhmedov RU2, Salyakhova EV1 and Sayfutdinov Rafik Galimzyanovich1,2*
11Kazan State Medical Academy - Branch Campus of the Federal State Budgetary Educational Institution of Further Professional Education “Russian Medical Academy of Continuing Professional Education of the Ministry of Healthcare of the Russian Federation (KSMA - Branch Campus of the FSBEI FPE RMACPE MOH Russia), Butlerov Street, Kazan, RT, Russia
22City Clinical Hospital, Lechebnia Street, Kazan, Russia
3Federal State Budgetary Educational Institution of Further Professional Education “Russian Medical Academy of Continuing Professional Education of the Ministry of Healthcare of the Russian Federation (Branch Campus of the FSBEI FPE RMACPE MOH Russia), Barrikadnaja Street, Moscow, Russia
*Corresponding Author: Sayfutdinov Rafik Galimzyanovich, Doctor of Medical Sciences, Head of the Department of Hospital and Polyclinic Therapy KSMA - Branch Campus of the FSBEI FPE RMACPE MOH Russia, Butlerov Street, Kazan, RT, Russia.
Received: October 02, 2021; Published: October 28, 2021


The Relevance of the Problem: At COVID-19, in addition to lung damage, there is a dysfunction of many systems and organs. Blood clotting is disrupted; markers of inflammation increase; liver, kidney, heart and other organs are affected. A number of studies have shown that the use of human placenta hydrolysate leads to positive clinical dynamics and improved laboratory parameters. Therefore, a more detailed study of the effectiveness of this drug in the treatment of COVID-19 seems relevant and practically significant.

The Purpose of the Work: To evaluate the effectiveness of human placenta hydrolysate in the treatment of COVID-19 in patients with moderate to severe disease.

Materials and Methods: 22 patients with COVID-19 were examined, divided into two groups. The first group was 11 people who received placental hydrolysate. The second - 11 people who did not receive the specified drug. The general and biochemical blood tests were examined. Respiratory function of the lungs was assessed by blood oxygenation (SpO2), and computed tomography (CT) of the chest organs. COVID-19 was confirmed by the detection of virus RNA in smears from the nasopharynx and oropharynx and/or biomaterial samples from the lower respiratory tract (in severe cases) in patients with suspected Covid-19 infection. The data is presented in the form of the arithmetic mean and its standard error (M ± m). The differences were considered statistically significant at p < 0.05.

Results and Discussion: Along with the clinical symptoms, the examined patients showed changes in the GBT, symptoms of gastrointestinal damage, liver dysfunction, signs of a "cytokine storm", kidney damage, and blood clotting disorders. The introduction of 6 ml of placental hydrolysate daily for 10 days intravenously drip had a positive effect on the general condition of patients and blood biochemical parameters.

Conclusion: Compared with the control, placental hydrolysate (laennec) has a more favorable effect on the dynamics of laboratory parameters, namely: there is a more significant and reliable improvement in the indicators on the drug, a higher percentage of changes in melons, and a shorter period of stay of patients in the hospital.

Keywords: Patients with COVID-19; Moderate; Severe; Treatment; Human Placenta Hydrolysate


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Citation: Sayfutdinov Rafik Galimzyanovich., et al. “Possibilities of Using Placenta Hydrolysate in Patients with COVID-19”. EC Gastroenterology and Digestive System 8.11 (2021): 91-101.

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