Research Article
Volume 9 Issue 1 - 2021
CT Colonography, the Revolutionary Imaging Tool in Detecting Colon Cancer and Extra Colonic Conditions, a Comparative Study with the Gold Standard Colonoscopy

George Bazoua1*, Joseph Alex2, Deepak Pai2, Mohammad Abdi3 and Hussein Hassan2

1Consultant General Surgeon with Interest in Colorectal Surgery, Department of General and Colorectal Surgery, Northern Lincolnshire and Goole NHS Foundation Trust, Diana Princess of Wales Hospital, Grimsby, England, UK
2Consultant Radiologist, Department of Radiology, Northern Lincolnshire and Goole NHS Foundation Trust, Diana Princess of Wales Hospital, Grimsby, England, UK
3Radiology Trainees, Department of Radiology, Northern Lincolnshire and Goole NHS Foundation Trust, Diana Princess of Wales Hospital, Grimsby, England, UK

*Corresponding Author: George Bazoua, Consultant General Surgeon with Interest in Colorectal Surgery, Department of General and Colorectal Surgery, Northern Lincolnshire and Goole NHS Foundation Trust, Diana Princess of Wales Hospital, Grimsby, England, UK.

Received: November 23, 2021; Published: December 31, 2021


Background: CT Colonography (CTC) has equivalent sensitivity and specificity to colonoscopy, provided it is performed to internationally agreed standards. It is essential to assess the quality of (CTC) service provision against these standards.

Aim: Evaluate the diagnostic performance of (CTC) in detecting colorectal cancer and polyps using conventional colonoscopy (CC) as the gold standard technique. Assess the sensitivity, specificity, positive and negative predictive value of CTC versus CC in each group and overall.

Methods: Retrospective review of 547 patients referred for (CTC) with colorectal symptoms between January 2013 to December 2013. 467 (85.4%) had (CTC) and 80 (14.6%) had (CTC) and colonoscopy. Colonoscopy and (CTC) findings were compared. Patients with negative (CTC) for cancer followed up in Somerset cancer register for 3.5 years.

Results: Gender distribution showed 42% males Vs 58% females with 511 (93.4%) good colonic distention compared to 36 (6.6%) poor distention. (CTC) was normal in 357 (65%), extra-colonic pathology noncancerous in 67 (12.2%), polyp detected in 54 (9.8%), failed (CTC) in 36 (6.5%), colorectal cancer found in 21 patients (3%), extra-colonic cancer in 7 (1.2%), severe diverticulitis in 5 patients (0.9%). Positive predictive value (PPV) was 97.4%, Negative predictive value (NPV) was 95.2%, Sensitivity 94.9%, Specificity and 97.6%. Findings matches Somerset cancer registry in 2017 with no cancer detected in those patients with normal (CTC).

Conclusion: (CTC) is a reliable minimally invasive imaging tool as compared to colonoscopy in detecting colonic polyps and cancer with additional benefits of detecting extra-colonic conditions.


Keywords: Screening CT Colonography; Colorectal Cancer; CTC vs Colonscopy


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Citation: George Bazoua., et al. “CT Colonography, the Revolutionary Imaging Tool in Detecting Colon Cancer and Extra Colonic Conditions, a Comparative Study with the Gold Standard Colonoscopy”. EC Gastroenterology and Digestive System 9.1 (2022): 37-46.

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