Research Article
Volume 9 Issue 4 - 2022
Endoscopic Variceal Ligation Compared with Sclerotherapy for Treatment of Bleeding Esophageal Varices in Decompensated Cirrhosis- A Single Center Experience
Hemanta Kumar Nayak, Rahul Karna and Premashis Kar*
Department of Medicine, Maulana Azad Medical College, New Delhi, India
*Corresponding Author: Premashis Kar, Department of Medicine, Maulana Azad Medical College, New Delhi, India.
Received: December 23, 2021; Published: March 15, 2022


Objectives: Acute variceal bleeding is a catastrophic complication of liver cirrhosis. We aim to compare the efficacy of endoscopic variceal band ligation (EVL) and endoscopic injection sclerotherapy (EIS), the two most commonly used procedures used for therapy of variceal hemorrhage.

Materials and Methods: We conducted a retrospective analysis from hospital records in 111 patients in EVL arm and 103 patients in EIS arm. Primary endpoints of the study were incidence of rebleeding and death. Secondary endpoints were adverse effects of EVL and EIS, variceal eradication and variceal recurrence after eradication.

Results: The initial hemostat rate was similar in both groups (EVL, 94.6%; EIS, 96.1%). However, the EVL group required fewer mean sessions to eradicate varices (4.4 ± 1.6 vs. 5.8 ± 2.1), fewer blood transfusions, lower rates of rebleeding (14.4% vs. 26.2%), lower mortality (7.2% vs. 13.6%) and higher variceal eradication after 12 months follow-up (86% vs. 73%) compared to the EIS group.

Conclusion: EVL scored over EIS in terms of efficacy, complications, and mortality. The probability of patients remaining bleed-free was higher (p < 0.01) in the EVL group than the EIS group. Hence, EVL is a safer and more effective option than EIS for initial and long-term control of bleeding.


Keywords: Cirrhosis; Endoscopic Variceal Ligation; Endoscopic Sclerotherapy; Variceal Bleed


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Citation: Premashis Kar., et al. “Endoscopic Variceal Ligation Compared with Sclerotherapy for Treatment of Bleeding Esophageal Varices in Decompensated Cirrhosis- A Single Center Experience”. EC Gastroenterology and Digestive System 9.4 (2022): 01-06.

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