Mini Review
Volume 9 Issue 5 - 2022
Aging and the Impact on the Intestinal Microbiota
Carlos Castañeda Guillot1,2*
1Emeritus Professor, Faculty of Medicine, Autonomous Regional University of Los Andes, Ambato, Ecuador
2Consulting Professor, Senior Research, Medical Faculty Calixto Garcia, Medical University of La Habana, Cuba
*Corresponding Author: Carlos Castañeda-Guillot, Emeritus Professor, Faculty of Medicine, Autonomous Regional University of Los Andes, Ambato, Ecuador.
Received: February 09, 2022; Published: April 22, 2022




Abstract

The intestinal microbiota participates, with its various actions in the function of intestinal homeostasis and the protection of the intestinal immune balance. The objective of this review article is to draw attention to the interaction of the intestinal microbiota with aging, the changes that occur during its process, and the role of diet in maintaining the physiological process for a healthy state of the intestinal microbiota. The role of nutrients, and especially of probiotic foods and those with a prebiotic effect, has been reviewed.

Keywords: Gut Microbiota; Aging; Diet; Food Components

References

  1. Rowland I., et al. “Gut microbiota functions, metabolism of nutrents and other food components”. European Journal of Nutrition1 (2018): 1-24.
  2. Sherwin E., et al. “Recent development in understanding the role of gut microbiota in brain health and disease”. Annals of the New York Academy of Sciences1 (2018): 5-25.
  3. Buford TW. “Trust your gut: The gut microbiome in age-related inflammation, health, and disease”. Microbiome80 (2017): 1-11.
  4. Leite G., et al. “Age and the aging process significantly alter the small bowel microbiome”. Cell Repots13 (2021): 109765.
  5. Cryan JF and O'Riordan KJ. “The microbiota-gut-brain axis”. Physiological Reviews4 (2019): 1877-2013.
  6. Maiuolo J Gliozzi M., et al. “The Contribution of Gut Microbiota–Brain Axis in the Development of Brain Disorders”. Frontiers in Neuroscience (2021).
  7. Han B., et al. “Microbial genetic composition tunes lost longevity”. Cell13 (2017): 1249-1262.
  8. Aw W and Fukuda S. “Understanding the role of the gut ecosystem in diabetes mellitus”. Journal of Diabetes Investigation1 (2018): 5-12.
  9. Cunningham AL., et al. “A review on gut microbiota: a central factor in the pathophysiology of obesity”. Lipids in Health and Disease 20 (2021): 65.
  10. Castañeda-Guillot C. “Fatty Liver disease: a new pandemic?” EC Gastroenterology and Digestive System5 (2021): 15-19.
  11. Alam MT., et al. “Microbial imbalance in inflammatory bowel disease patients at different taxonomic levels”. Gut Pathogens 12 (2020): 1.
  12. Flemer B., et al. “The oral microbiota in colorectal cancer is distinctive and predictive”. Gut8 (2018): 1454-1463.
  13. Tang WH and Hanzen SL. “The Gut Microbiome and its Role in Cardiovascular Diseases”. Circulation11 (2017): 1008-1010.
  14. Cenit MC., et al. “Influence of gut microbiota on neuropsychiatric disorders”. World Journal of Gastroenterology 23.30 (2017): 5486-5498.
  15. Huang T-T., et al. “Current Understanding of Gut Microbiota in Mood Disorders: An Update of Human Studies”. Frontiers in Genetics (2019).
  16. Cattaneo A., et al. “Association of brain amyloidosis with pro-inflammatory gut bacterial taxa and peripheral inflammation markers in cognitively impaired elderly”. Neurobiol Aging 49 (2017): 60-68.
  17. Castañeda-Guillot C. “Gut dysbiosis”. EC Gastroenterology and Digestive System3 (2020): 01-04.
  18. Negpal R., et al. “Gut microbiome and aging: Physiological and mechanistic insights”. The Journal of Nutrition, Health and Aging4 (2018): 267-285.
  19. Itani T., et al. “Establishment and development of the intestinal microbiota”. Anaerobe 43 (2017): 4-14.
  20. Leite G., et al. “Age and the axing process significantly alterthe small bowel microbioe”. Cell Reports13 (2021): 109765.
  21. Lilly DM and Stillwell RH. “Probiotics promoving factors produced by microorganisms”. Science 147 (1965): 747-748.
  22. Guarner F., et al. “Probiotics and Prebiotics”. World Gastroenterology Organization (2017).
  23. Castañeda-Guillot C. “Probiotics. Update”. Revista Cubana de Pediatría2 (2018): 286-298.
  24. Zommiti M., et al. “Update of Probiotics in Human World: A Nonstop Source of Benefactions till the End of Time”. Microorganisms12 (2020).
  25. Gibson GR., et al. “DIetary modulation of the human colonic microbiota: introducing the concept of prebiotics”. Journal of Nutrition6 (1995): 1401-1412.
  26. Wang Y., et al. “Probiotic supplements: hope or hype?” Frontiers in Microbiology (2020).
  27. Kim S and Jazwinski SM. “The Gut Microbiota and Healthy Aging: A Mini-review”. Gerontology 64 (2018): 513-520.
  28. Mackowiak PA. “Recycling Metchnikoff: Probiotics, the intestinal microbiome and the quest for long life”. Frontiers in Public Health 1 (2013): 52.
Citation: Carlos Castañeda Guillot. “Aging and the Impact on the Intestinal Microbiota”. EC Gastroenterology and Digestive System 9.5 (2022): 21-26.

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