Case Report
Volume 7 Issue 3 - 2020
Immunohistochemical Study on HER-2 Receptor Activity in the Patient with Signet Ring Cell Gastric Carcinoma as Well as its Prognostic and Therapeutical Significance. Case Report and Review of the Literature
Vuka Katić1*, Ivan Ilić1, Suzana Branković2, Marko Gmijović1, Aleksandar Petrović1, Danilo Zdravković3, Maja Petrovski4 and Dimitrije Pavlović1
1Medical Faculty of Niš University, Nis, Serbia
2Ophthalmology Department, Belgrade, Serbia
3Department of Microbiology, Kruševac Hospital, Serbia
4Community Health Centar, Niš, Serbia
*Corresponding Author: Vuka Katić, Medical Faculty of Niš University, Nis, Serbia.
Received: November 25, 2019; Published: February 28, 2020


Human epidermal growth factor receptor-2 (HER-2) is related to pathogenesis and poor outcome of numerous types of carcinomas, including gastric carcinoma. Gastric cancer patients with HER 2 positivity have become potential candidates for targeted therapy with trastuzumab, that has been confirmed by this case.

Keywords: Signet Ring Cell Carcinoma; HER-2; Histology; Mucins; Immunohistochemistry; Therapy


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Citation: Vuka Katić., et al. “Immunohistochemical Study on HER-2 Receptor Activity in the Patient with Signet Ring Cell Gastric Carcinoma as Well as its Prognostic and Therapeutical Significance. Case Report and Review of the Literature”. EC Gastroenterology and Digestive System 7.3 (2020): 01-04.

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