Review Article
Volume 7 Issue 2 - 2020
Overview of Transjugular Intrahepatic Portosystemic Shunts
Alaa Rashad H Hassanein1*, Yasser Abdulsalam Alquliti2, Howaida Shaker Saati3, Ahmed Taher Bo Khamseen4, Asaad Saleh Radwan5, Wed Ahmed Mohammed Alayyafi1, Sukaynah Ahmed AL Sultan6, Khalid Mohammed Alshehri7, Bodoor Salmi Almotairi2, Ahmed Essa Abdullah Alsukairi8, Ahmed Ali Almeshari9 and Abdullah Saud Al-Thani10
1Ibn Sina Medical College, Saudi Arabia
2Taibah University, Saudi Arabia
3King Saud bin Abdulaziz University for Health Sciences, Saudi Arabia
4Qatif Central Hospital, Saudi Arabia
5King Abdulaziz Hospital, Saudi Arabia
6Arabian Gulf University, Saudi Arabia
7King Fahad Armed Forces Hospital, Saudi Arabia
8Dammam University, Saudi Arabia
9Dammam Medical Complex, Saudi Arabia
10King Faisal University, Saudi Arabia
*Corresponding Author: Alaa Rashad H Hassanein, Ibn Sina Medical College, Saudi Arabia.
Received: January 12, 2020; Published: January 22, 2020


Introduction: Transjugular intrahepatic portosystemic shunt (TIPS) is a fabricated network within the liver developed utilizing inflow portal vein as well as the discharge of the hepatic vein. Throughout current years technological renovations and brand-new understandings of pathophysiology have customized indicators for TIPS. It is typically approved that the transjugular intrahepatic portosystemic shunt treatment has reduced morbidity and death rates better than those of medical shunting. Difficulties are classified per those about transhepatic needle slit, transvenous accessibility to the portal capillary, portal venous cannulation, portosystemic shunting, as well as contrast material. Leaving out hepatic encephalopathy as well as postponed constriction or occlusion of the shunt, much less than 10% can be anticipated for TIPS side-effects. Along with these technological enhancements, standard pathophysiological expertise and hence likewise the indicators for TIPS have actually increased in recent times. This review article talks about the existing state of the understanding of TIPS, technological breakthroughs, problems, and also standards of patient status.

Aim: In this inclusive review, we look into transjugular intrahepatic portosystemic shunts and the management approaches related to this procedure.

Keywords: TIPS; Hepatic Vein; Liver Varices; Portal Vein


  1. Amesur NB and Novelli P. “Transjugular Intrahepatic Portosystemic Shunt”. Stat Pearls. Treasure Island (FL) (2019).
  2. Rossle M. “TIPS: 25 years later”. Journal of Hepatology 59 (2013): 1081-1093.
  3. Villanueva C., et al. “Development of hyperdynamic circulation and response to beta-blockers in compensated cirrhosis with portal hypertension”. Hepatology 63 (2016): 197-206.
  4. Freedman AM., et al. “Complications of transjugular intrahepatic portosystemic shunt: a comprehensive review”. Radiographics 13 (1993): 1185-1210.
  5. De Franchis R and Baveno VIF. “Expanding consensus in portal hypertension: Report of the Baveno VI Consensus Workshop: Stratifying risk and individualizing care for portal hypertension”. Journal of Hepatology 63 (2015): 743-752.
  6. Berres ML., et al. “Chemokine (C-X-C motif) ligand 11 levels predict survival in cirrhotic patients with transjugular intrahepatic portosystemic shunt”. Liver International 36 (2016): 386-394.
  7. Zahn A., et al. “Budd-Chiari syndrome: long term success via hepatic decompression using transjugular intrahepatic porto-systemic shunt”. BMC Gastroenterology 10 (2010): 25.
  8. Boyer TD and Haskal ZJ, “American Association for the Study of Liver D. The Role of Transjugular Intrahepatic Portosystemic Shunt (TIPS) in the Management of Portal Hypertension: update 2009”. Hepatology 51 (2010): 306.
  9. David A., et al. “Ultrasonographic guidance for portal vein access during transjugular intrahepatic portosystemic shunt (TIPS) placement”. Diagnostic and Interventional Imaging 100 (2019): 445-453.
  10. Khan F., et al. “Timing of Transjugular Intrahepatic Portosystemic Stent-shunt in Budd-Chiari Syndrome: A UK Hepatologist's Perspective”. Journal of Translational Internal Medicine 6 (2018): 97-104.
  11. Ripamonti R., et al. “Transjugular intrahepatic portosystemic shunt-related complications and practical solutions”. Seminars in Interventional Radiology 23 (2006): 165-176.
  12. Sauer P., et al. “Phenprocoumon for prevention of shunt occlusion after transjugular intrahepatic portosystemic stent shunt: a randomized trial”. Hepatology 24 (1996): 1433-1436.
  13. Eesa M and Clark T. “Transjugular intrahepatic portosystemic shunt: state of the art”. Seminars in Roentgenology 46 (2011): 125-132.
  14. Jalan R., et al. “Analysis of prognostic variables in the prediction of mortality, shunt failure, variceal rebleeding and encephalopathy following the transjugular intrahepatic portosystemic stent-shunt for variceal haemorrhage”. Journal of Hepatology 23 (1995): 123-128.
  15. Leng X., et al. “Comparison of transjugular intrahepatic portosystemic shunt for treatment of variceal bleeding in patients with cirrhosis with or without spontaneous portosystemic shunt”. European Journal of Gastroenterology and Hepatology 31 (2019): 853-858.
Citation: Alaa Rashad H Hassanein., et al. “Overview of Transjugular Intrahepatic Portosystemic Shunts”. EC Gastroenterology and Digestive System 7.2 (2020): 01-07.

PubMed Indexed Article

EC Pharmacology and Toxicology
LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.

PMID: 31143884 [PubMed]

PMCID: PMC6536005

EC Pharmacology and Toxicology
Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.

PMID: 31565701 [PubMed]

PMCID: PMC6764777

EC Neurology
Differences in Rate of Cognitive Decline and Caregiver Burden between Alzheimer's Disease and Vascular Dementia: a Retrospective Study.

PMID: 27747317 [PubMed]

PMCID: PMC5065347

EC Pharmacology and Toxicology
Will Blockchain Technology Transform Healthcare and Biomedical Sciences?

PMID: 31460519 [PubMed]

PMCID: PMC6711478

EC Pharmacology and Toxicology
Is it a Prime Time for AI-powered Virtual Drug Screening?

PMID: 30215059 [PubMed]

PMCID: PMC6133253

EC Psychology and Psychiatry
Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.

PMID: 30417173 [PubMed]

PMCID: PMC6226033

EC Anaesthesia
Arrest Under Anesthesia - What was the Culprit? A Case Report.

PMID: 30264037 [PubMed]

PMCID: PMC6155992

EC Orthopaedics
Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.

PMID: 30198026 [PubMed]

PMCID: PMC6124505

EC Pulmonology and Respiratory Medicine
Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012.

PMID: 30294723 [PubMed]

PMCID: PMC6169793

EC Dental Science
Important Dental Fiber-Reinforced Composite Molding Compound Breakthroughs

PMID: 29285526 [PubMed]

PMCID: PMC5743211

EC Microbiology
Prevalence of Intestinal Parasites Among HIV Infected and HIV Uninfected Patients Treated at the 1o De Maio Health Centre in Maputo, Mozambique

PMID: 29911204 [PubMed]

PMCID: PMC5999047

EC Microbiology
Macrophages and the Viral Dissemination Super Highway

PMID: 26949751 [PubMed]

PMCID: PMC4774560

EC Microbiology
The Microbiome, Antibiotics, and Health of the Pediatric Population.

PMID: 27390782 [PubMed]

PMCID: PMC4933318

EC Microbiology
Reactive Oxygen Species in HIV Infection

PMID: 28580453 [PubMed]

PMCID: PMC5450819

EC Microbiology
A Review of the CD4 T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population

PMID: 26280024 [PubMed]

PMCID: PMC4533840

EC Neurology
Identifying Key Symptoms Differentiating Myalgic Encephalomyelitis and Chronic Fatigue Syndrome from Multiple Sclerosis

PMID: 28066845 [PubMed]

PMCID: PMC5214344

EC Pharmacology and Toxicology
Paradigm Shift is the Normal State of Pharmacology

PMID: 28936490 [PubMed]

PMCID: PMC5604476

EC Neurology
Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia

PMID: 28713879 [PubMed]

PMCID: PMC5510658

EC Neurology
Unilateral Frontosphenoid Craniosynostosis: Case Report and a Review of the Literature

PMID: 28133641 [PubMed]

PMCID: PMC5267489

EC Ophthalmology
OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling

PMID: 29333536 [PubMed]

PMCID: PMC5766278

EC Neurology
Longer Duration of Downslope Treadmill Walking Induces Depression of H-Reflexes Measured during Standing and Walking.

PMID: 31032493 [PubMed]

PMCID: PMC6483108

EC Microbiology
Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.

PMID: 30957099 [PubMed]

PMCID: PMC6448571

EC Nutrition
Food Insecurity among Households with and without Podoconiosis in East and West Gojjam, Ethiopia.

PMID: 30101228 [PubMed]

PMCID: PMC6086333

EC Ophthalmology
REVIEW. +2 to +3 D. Reading Glasses to Prevent Myopia.

PMID: 31080964 [PubMed]

PMCID: PMC6508883

EC Gynaecology
Biomechanical Mapping of the Female Pelvic Floor: Uterine Prolapse Versus Normal Conditions.

PMID: 31093608 [PubMed]

PMCID: PMC6513001

EC Dental Science
Fiber-Reinforced Composites: A Breakthrough in Practical Clinical Applications with Advanced Wear Resistance for Dental Materials.

PMID: 31552397 [PubMed]

PMCID: PMC6758937

EC Microbiology
Neurocysticercosis in Child Bearing Women: An Overlooked Condition in Mozambique and a Potentially Missed Diagnosis in Women Presenting with Eclampsia.

PMID: 31681909 [PubMed]

PMCID: PMC6824723

EC Microbiology
Molecular Detection of Leptospira spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.

PMID: 31681910 [PubMed]

PMCID: PMC6824726

EC Neurology
Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases.

PMID: 31528859 [PubMed]

PMCID: PMC6746603

EC Psychology and Psychiatry
Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?

PMID: 31276119 [PubMed]

PMCID: PMC6604646

EC Anaesthesia
Real Time Locating Systems and sustainability of Perioperative Efficiency of Anesthesiologists.

PMID: 31406965 [PubMed]

PMCID: PMC6690616

EC Pharmacology and Toxicology
A Pilot STEM Curriculum Designed to Teach High School Students Concepts in Biochemical Engineering and Pharmacology.

PMID: 31517314 [PubMed]

PMCID: PMC6741290

EC Pharmacology and Toxicology
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese.

PMID: 31633124 [PubMed]

PMCID: PMC6800226

EC Neurology
Research Volunteers' Attitudes Toward Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.

PMID: 29662969 [PubMed]

PMCID: PMC5898812

EC Pharmacology and Toxicology
Hyperbaric Oxygen Therapy for Alzheimer's Disease.

PMID: 30215058 [PubMed]

PMCID: PMC6133268

News and Events

July Issue Release

We always feel pleasure to share our updates with you all. Here, notifying you that we have successfully released the July issue of respective journals and the latest articles can be viewed on the current issue pages.

Submission Deadline for Upcoming Issue

ECronicon delightfully welcomes all the authors around the globe for effective collaboration with an article submission for the upcoming issue of respective journals. Submissions are accepted on/before July 19, 2022.

Certificate of Publication

ECronicon honors with a "Publication Certificate" to the corresponding author by including the names of co-authors as a token of appreciation for publishing the work with our respective journals.

Best Article of the Issue

Editors of respective journals will always be very much interested in electing one Best Article after each issue release. The authors of the selected article will be honored with a "Best Article of the Issue" certificate.

Certifying for Review

ECronicon certifies the Editors for their first review done towards the assigned article of the respective journals.

Latest Articles

The latest articles will be updated immediately on the articles in press page of the respective journals.