Volume 9 Issue 12 - 2020
Polycystic Ovary Syndrome (PCOS): The Pros and Cons of Various Diagnostic Criteria
Ashutosh Halder* and Hemant Kumar
Department of Reproductive Biology, AIIMS, New Delhi, India
*Corresponding Author: Ashutosh Halder, Professor and Head, Department of Reproductive Biology, AIIMS, New Delhi, India.
Received: November 25, 2020; Published: November 28, 2020

Classical polycystic ovarian syndrome (PCOS) is characterized by hyperandrogenism (clinical and/or biochemical), chronic ovulatory dysfunction (oligo-ovulation and/or anovulation) and polycystic ovarian morphology (polycystic and/or enlarged ovary). PCOS is the most common reproductive endocrine disorder in women of reproductive age with a prevalence between 5-15% depending on diagnostic criteria used [1,2].


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  6. Vallisneri A. “Istoria della Generazione dell’Uomo I, degli Animali, se Sia da’ Vermicelli Spermatici, o dalle uova”. Venezia (Italy): Appresso Gio Gabbriel Hertz (1721): 146.
  7. Chereau A. “Mémoires pour servir à l’étude des maladies des ovaires. Paris (France): Fortin, Masson and Cie (1844): 9-3.e1.
  8. Bulius G and Kretschmar C. “Angiodystrophia”. Stuttgart: Verlag von Ferdinand Enke (1897).
  9. Yen SSC., et al. “Inappropiate secretion of follicle-stimulating hormone and luteinizing hormone in polycystic ovarian disease”. The Journal of Clinical Endocrinology and Metabolism 30 (1970): 435-442.
  10. Rebar R., et al. “Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome”. The Journal of Clinical Endocrinology and Metabolism 57 (1976): 1320-1329.
  11. Evans TN and Riley GM. “Polycystic ovarian disease (Stein-Leventhal syndrome); etiology and rationale for surgical treatment”. Obstetrics and Gynecology 12 (1958): 168-179.
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  14. Keettel WC., et al. “Observations on the polycystic ovary syndrome”. American Journal of Obstetrics and Gynecology 73 (1957): 954-962.
  15. Joshi B., et al. “A cross-sectional study of polycystic ovarian syndrome among adolescent and young girls in Mumbai, India”. The Indian Journal of Endocrinology and Metabolism 18 (2014): 317-324.
  16. Wiweko B., et al. “Anti-mullerian hormone as a diagnostic and prognostic tool for PCOS patients”. The Journal of Assisted Reproduction and Genetics 31 (2014): 1311-1316.
  17. The Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group. “Revised consensus on diagnostic criteria and long-term health risk related to polycystic ovary syndrome (PCOS)”. Human Reproduction 19 (2004): 41-47.
  18. Azziz R., et al. “Positions statement: Criteria for defining polycystic ovary syndrome as a predominantly hyperandrogenic syndrome: An Androgen Excess Society guideline”. The Journal of Clinical Endocrinology and Metabolism 91 (2006): 4237-4245.
  19. Goodman NF., et al. “American Association of Clinical Endocrinologists (AACE); American College of Endocrinology (ACE); Androgen Excess and PCOS Society (AES). American association of clinical endocrinologists, American college of endocrinology, and Androgen excess and PCOS society disease state clinical review: guide to the best practices in the evaluation and treatment of polycystic ovary syndrome--part 1”. Endocrine Practice 21 (2015): 1291-1300.
  20. National Institutes of Health. Evidence-based Methodology Workshop on Polycystic Ovary Syndrome (2012).
  21. Dewailly D. “Diagnostic criteria for PCOS: Is there a need for a rethink?” Best Practice and Research in Clinical Obstetrics and Gynaecology 37 (2016): 5-11.
Citation: Ashutosh Halder and Hemant Kumar. “Polycystic Ovary Syndrome (PCOS): The Pros and Cons of Various Diagnostic Criteria”.EC Gynaecology 9.12 (2020): 39-41.

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