Research Article
Volume 9 Issue 12 - 2020
Hemoglobin Vs Serum Ferritin as Assessors of Iron Deficiency Anemia, Preference for Age and Gender Groups, Using Inferential, Binary Logistic Regression and Bivariate Correlation Statistics
Hamzullah Khan1*, Neelum Shehzadi2, Khalid Khan3, Mohammad Khalid4, Saadullah Afridi5 and Sarwat6
1Associate Professor of Hematology, Nowshera Medical College, Nowshera, Pakistan
2Associate Professor of Gynecology and Obstetrics, Nowshera Medical College, Nowshera, Pakistan
3Assistant Professor of Pediatrics, Nowshera Medical College, Nowshera, Pakistan
4Associate Professor of Medicine, Nowshera Medical College, Nowshera, Pakistan
5Director Public Health, Sarhad University, Peshawar, Pakistan
6Assistant Professor of Gynecology and Obstetrics, Bacha khan Medical College, Mardan, Pakistan
*Corresponding Author: Hamzullah Khan, Associate Professor of Hematology, Director Research and Development, Nowshera Medical College, Nowshera, Pakistan.
Received: June 26, 2020; Published: November 28, 2020




Abstract

Objectives: To assess the hemoglobin vs serum ferritin as predictors of Iron deficiency anemia, using binary logistic regression, bivariate correlation and inferential statistics.

Materials and Methods: This cross sectional study was conducted in the Pathology department, Qazi Hussain Ahmed Medical Complex, Medical Teaching Institution Nowshera, from 20th February 2019 to 21st January 2020. Relevant information’s were entered in SPPS Version 25th for descriptive and inferential analysis.

Results: Out of 381,149 patients enrolled with Hb < 11 g/dl. Twenty (13.4%) were males and 129 (86.6%) females. Mean age with SD was 30 ± 6.2 years. The Mean Ferritin level with SD was 64.35 ± 33.45. The Mean Hemoglobin level with SD was 9 ± 1.8 g/dl. There was a statistically significant difference in Mean ± SD hemoglobin between gender groups (8.5 g/dl ± 1.43-Males) (9.14g/dl ± 1.86-Females) (p = 0.053) on Independent Sample Test and vice versa for ferritin. Ninety (60.4%) patients had serum ferritin less than 15 ng/ml. The Positive Predictive Value (PPV) of Hemoglobin as predictors of IDA was 39.1%, while 60.4% for serum ferritin. There was a significant positive relationship between Hb% and ferritin (p = 0.01, r = 0.4). There was an inverse relation of Hb% and ferritin with an increase in age (p = 0.185, r = -0.1), (p = 0.38, r = -.07) respectively. Odds ratio of 3.2 times was noted for low iron stores in patient with low hemoglobin (p = 0.01, OR-3.2). The probability of ferritin less than 15ng/ml was 2.7 times in female gender (p = 0.022, OR = 2.7).

Conclusion: We concluded that the PPV of serum ferritin is higher than Hb% for prediction of iron deficiency anemia.

Keyword: Hb% vs Ferritin; Iron Deficiency Anemia; Predictor of IDA

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Citation: Hamzullah Khan., et al. “Hemoglobin Vs Serum Ferritin as Assessors of Iron Deficiency Anemia, Preference for Age and Gender Groups, Using Inferential, Binary Logistic Regression and Bivariate Correlation Statistics”. EC Gynaecology 9.12 (2020): 42-49.

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