Research Protocol
Volume 9 Issue 1 - 2020
Experience of Compression Elastography and Contrast-Enhanced Ultrasound Examination in Differential Diagnosis of Primary and Metastatic Ovarian Tumors in Uterine Cancer Patients
Chekalova MA and Borisova MI*
National Medical Research Center of Oncology Named After N. N. Blokhina of the Ministry of Health of the Russian Federation, Moscow, Russia
*Corresponding Author: Borisova MI, National Medical Research Center of Oncology Named After N. N. Blokhina of the Ministry of Health of the Russian Federation, Moscow, Russia.
Received: November 29, 2019; Published: January 30, 2020


Objective: To study the possibilities of tissue elastography (RTE) and contrast-enhanced ultrasound (CEUS) in the differential diagnosis of primary and metastatic ovarian tumors in uterine cancer patients.

Materials and Methods: The results of observations of 8 patients were analyzed.

Results: We identified 8 patients with ovarian tumors, of whom 4 had synchronous primary cancers of the endometrium (synchronous group) and ovary and 4 had endometrial cancer with ovarian metastasis (metastasis group). Ovarian tumors in the synchronous group were more often unilateral, the structure of the ovarian tumor is more often multilocular-solid with uneven, clear contours, the size of the ovaries exceeds 6.0 cm and the ovaries were mapped with 4 types of elastograms during RTE. In this group dissemination of the process was not detected. Ovarian tumors in metastasis group were both bilateral and unilateral, represented by solid formations with clear, even contours, ovarian size did not exceed 6.0 cm, disseminated process was revealed in half of the cases (metastases in the greater omentum and in the retroperitoneal lymph nodes). With RTE solid formations in the structure of the ovaries were mapped mainly by type 5 elastograms. With CEUS in areas of a solid structure a rapid accumulation of the contrast agent in the arterial phase and its rapid excretion into the venous phase was revealed, only the contours of the walls and septum were visualized in the late phase with the multilocular-solid structure of the ovary.

Conclusion: When we conduct an ultrasound examination of patients with a uterine cancer, a thorough study of the structure of the ovaries is important for timely diagnosis of the tumor. Further development of differential diagnostic criteria for macrometastases and synchronous ovarian tumors using modern ultrasound technologies is a promising task, since this information is necessary to correct the volume of surgery in this category of patients.

Keywords: Endometrial Cancer; Primary Multiple Tumor; Ultrasound Examination; Tissue Elastography


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Citation: Chekalova MA and Borisova MI. “Experience of Compression Elastography and Contrast-Enhanced Ultrasound Examination in Differential Diagnosis of Primary and Metastatic Ovarian Tumors in Uterine Cancer Patients”. EC Gynaecology 9.2 (2020): 01-10.

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