Research Article
Volume 17 Issue 10 - 2021
Potassium Isomerized Linoleate Satisfies EPA MB-35-00 for Surface Disinfection of Candida auris (AR-0381) and Candida albicans (ATCC 10231)
David G Changaris* and Anne L Carenbauer
Robert S. Levy Lipid Laboratory, Department of Microbiology, Ceela Naturals LLC, Louisville, Kentucky, United States of America
*Corresponding Author: David G Changaris, Robert S. Levy Lipid Laboratory, Department of Microbiology, Ceela Naturals LLC, Louisville, Kentucky, United States of America.
Received: July 16, 2021; Published: September 30, 2021




Abstract

Long-standing United States Environmental Protection Agency regulatory perspectives hold that all plant oil salts lack direct antimicrobial capacity. We show that one plant oil salt, potassium isomerized linoleate, a C18 conjugated diene (the potassium salt of isomerized linoleic acid (UNII: 70S2158RCI)) at 0.42M exceeds the required 5 log kill rate within 1 minute for Candida auris (AR-0381). Similar testing of this plant oil salt against Candida albicans (ATCC 10231) also demonstrated greater than 5 log kill rates at 1 minute of exposure. In the case of C. albicans, 5 log kill rates could be obtained at concentrations as low as 98 mM when extending exposures to 10 min. Potassium hexadiene (potassium sorbate), another conjugated diene, had negligible kill rates when tested at the same pH conditions and concentrations as potassium isomerized linoleate. The presence of the conjugated diene alone did not elicit any rapid antimicrobial effects.

 

Keywords: C. auris; Potassium Isomerized Linoleate; Surface Sanitization; EPA MB-35-00

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Citation: David G Changaris and Anne L Carenbauer. Potassium Isomerized Linoleate Satisfies EPA MB-35-00 for Surface Disinfection of Candida auris (AR-0381) and Candida albicans (ATCC 10231). EC Microbiology 17.10 (2021): 26-34.

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