Research Article
Volume 18 Issue 9 - 2022
Evaluation of Prediabetes in High Risk Population of Kashmir Valley
Javid A Khan1, Nissar ul Hassan2, Waseem A Qureshi3*, Masood Tanvir4, Adil Ashraf5 and Kadri SM6
1Registrar, Postgraduate Department of Medicine, Government Medical College, Srinagar, Jammu and Kashmir, India
2Assistant Professor, Postgraduate Department of Medicine, Government Medical College, Srinagar, Jammu and Kashmir, India
3Physician and Registrar Academics, Government Medical College, Srinagar, Jammu and Kashmir, India
4Professor and Head, Postgraduate Department of Medicine, Government Medical College, Srinagar, Jammu and Kashmir, India
5Registrar, Postgraduate Department of Medicine, Govt. Medical College, Srinagar, Jammu and Kashmir, India
6State Epidemiologist, Government Medical College, Srinagar, Jammu and Kashmir, India
*Corresponding Author: Waseem Qureshi, Physician and Registrar Academics, Government Medical College, Srinagar, Jammu and Kashmir, India.
Received: July 21, 2022; Published: August 24, 2022




Abstract

Background: To evaluate pre diabetes and diabetes in patients with clinical risk factors and or symptoms who have been previously undiagnosed.

Methods: A cross-sectional cohort study of 783 patients, carried at a tertiary health care centre using diagnostic tools of oral glucose challenge test (GCT), overnight fat standard oral glucose tolerance test (OGTT) and HbA1C estimation and criteria of standard guidelines applied for diagnosis of individual at risk of prediabetes and diabetes.

Results: Among the studied subjects, 588 (75.1%) were hypertensive, 67 (8.6%) had history of vascular disease, 84 (10.7%) had dyslipidemia and 78 (10%) carried family history of diabetes. On GCT, 266 (34%) subjects had levels of plasma glucose more than cut off of 140 mg/dl. A high sensitivity (92.59%), specificity (84.56%) was seen among diabetes, while as it was 75.58% and 84.56% among the subjects with pre-diabetes, and HbA1c > 5.5% was observed in 298 (38.1%) patients. The diabetics had mean BMI of 27.75 kg/m2 compared to 26.04 kg/m2 in pre-diabetics and mean age for diabetic and pre-diabetics was 52.68 and 51.7 years, respectively.

Conclusion: GCT screening would be an accurate, convenient and relatively in expensive way to detect pre-diabetes and previously unrecognized diabetes. Large scale surveys are suggested for better outcome.

Keywords: Diabetes; Pre-Diabetes; Oral Glucose Tolerance Test; Glycosylated Hemoglobin

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Citation: Waseem Qureshi., et al. “Evaluation of Prediabetes in High Risk Population of Kashmir Valley”. EC Microbiology 18.9 (2022): 27-32.

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