Research Article
Volume 16 Issue 12 - 2021
Evaluation of the Gastrointestinal Tolerability of Fibersmart®, a Novel Dietary Fiber, Using a Randomized Controlled Trial in Healthy Men and Women

Shaun Y M Teo1,2* and Timothy J Fairchild1,2

1Discipline of Exercise Science, Murdoch University, Perth, WA, Australia
2Associate Professor, Centre for Molecular Medicine and Innovative Therapeutics, Murdoch University, Perth, WA, Australia
*Corresponding Author: Shaun Y M Teo, Discipline of Exercise Science, Murdoch University, Perth, WA, Australia.
Received: October 05, 2021; Published: November 30, 2021




Abstract

Dietary fiber is integral to a healthful diet and the promotion of dietary fiber remains a key global health priority. Despite these efforts, most of the global population do not meet the dietary fiber intake recommendations. FiberSmart® is a type of resistant starch which may be added to food products to increase their dietary fiber content. The purpose of this randomized controlled trial was to determine the gastrointestinal (GI) tolerability of FiberSMART® consumption in generally healthy study volunteers. Forty generally healthy adults were randomized and allocated into either the intervention (n = 20; 27.8 ± 8.0 years; BMI: 26.6 ± 4.4; female: 8) or control (n = 20; 28.4 ± 11.4 years; BMI: 24.5 ± 4.6; female: 7) condition. Each group completed three phases of seven days each, separated by a 21-day wash-out. Participants in the intervention condition received an escalating dose of 10 g/day, 30 g/day and 50 g/day of FiberSMART® consumed in a single dose on each day, while those in the control condition received placebo (flavored drink without addition of FiberSMART®) on each day. Thirty-eight participants completed the trial (n = 19 in each condition). There were no significant between-group differences (p = .376) in the GI composite score over the three phases, and the reported symptoms were mild overall. Additionally, GI symptoms did not appear to increase across the escalating doses, which was supported by additional measures of GI tolerability including stool characteristics and self-reported quality of life. A dietary fiber supplement with good tolerability, as demonstrated in these studies of FiberSMART® in generally healthy adults, is of relevance to public health strategies aiming to increase global dietary fiber content.

Keywords: Dietary Fiber; Dietary Fibre; Health; Controlled Trial; RCT

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Citation: Shaun Y M Teo and Timothy J Fairchild. “Evaluation of the Gastrointestinal Tolerability of Fibersmart®, a Novel Dietary Fiber, Using a Randomized Controlled Trial in Healthy Men and Women”. EC Nutrition 16.12 (2021): 28-36.

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