Review Article
Volume 17 Issue 6 - 2022
Olive Oil: Nature’s Panacea
RE Carlson1 and JA von Fraunhofer2*
1Executive Director, Research and Analytical Sciences, D. Gary Young Research Institute, Lehi, UT, USA
2Professor Emeritus, University of Maryland, Baltimore, MD, USA
*Corresponding Author: JA von Fraunhofer, Professor Emeritus, University of Maryland, Baltimore, MD, USA.
Received: April 05, 2022; Published: May 27, 2022




Abstract

The differences between the various grades of commercially available olive oil are briefly reviewed together with the chemical characteristics of the major components of olive oil. The health benefits of the important polyphenols present in extra virgin olive oil, namely oleic acid, squalene and tocopherols are discussed.

Keywords: Olive Oil; Health Benefits; Polyphenols; Tocopherols

References

  1. Bellumori M., et al. “The EFSA health claim on olive oil polyphenols: acid hydrolysis validation and total hydroxytyrosol and tyrosol determination in Italian virgin olive oils”. Molecules 11 (2019): 2179.
  2. Parkinson L and Keast R. “Oleocanthal, a phenolic derived from virgin olive oil: A review of the beneficial effects on inflammatory disease”. International Journal of Molecular Sciences7 (2014): 12323-12334.
  3. Smith AB., et al. “Synthesis and assignment of absolute configuration of (−)-oleocanthal:  A potent, naturally occurring non-steroidal anti-inflammatory and anti-oxidant agent derived from extra virgin olive oils”. Organic Letters 22 (2005): 5075-5078.
  4. Cicerale S., et al. “Sensory characterization of the irritant properties of oleocanthal, a natural anti-inflammatory agent in extra virgin olive oils”. Chemical Senses4 (2009): 333-339.
  5. Beauchamp G., et al. “Ibuprofen-like activity in extra-virgin olive oil”. Nature 437 (2005): 45-46.
  6. Kotsiou A and Tesseromatis C. “Oleocanthal an extra-virgin olive oil bioactive component”. Journal of Medicinal Plants Studies 3 (2017): 95-100.
  7. Carlson RE and von Fraunhofer JA. “Oleocanthal and human health-An overview”. EC Nutrition3 (2022): 40-44.
  8. Marković AK., et al. “Hydroxytyrosol, tyrosol and derivatives and their potential effects on human health”. Molecules10 (2019): 1-29.
  9. Terés S., et al. “Oleic acid content is responsible for the reduction in blood pressure induced by olive oil”. Proceedings of the National Academy of Sciences of the United States of America 37 (2008): 13811-13816.
  10. Vassiliou EK., et al. “Oleic acid and peanut oil high in oleic acid reverse the inhibitory effect of insulin production of the inflammatory cytokine TNF-α both in vitro and in vivo systems”. Lipids in Health and Disease 8 (2009): 25.
  11. Sales-Campos H., et al. “An overview of the modulatory effects of oleic acid in health and disease”. Mini Reviews in Medicinal Chemistry2 (2013): 201-210.
  12. Kritchevsky D and Chen SC. “Phytosterols—health benefits and potential concerns: a review”. Nutrition Research 5 (2005): 413-428.
  13. Trautwein EA and Demonty I. “Phytosterols: natural compounds with established and emerging health benefits”. OCL 7 (2007): 259-266.
  14. Feng S., et al. “Phytosterols and their derivatives: Potential health-promoting uses against lipid metabolism and associated diseases, mechanism, and safety issues”. Comprehensive Reviews in Food Science and Food Safety4 (2020): 1243-1267.
  15. Woyengo T., et al. “Anticancer effects of phytosterols”. European Journal of Clinical Nutrition 7 (2009): 813-820.
  16. Narayan Bhilwade H., et al. “Squalene as novel food factor”. Current Pharmaceutical Biotechnology8 (2010): 875-880.
  17. Du Preez H. “Squalene - antioxidant of the future?” South African Journal of Natural Medicine 33 (2007): 106-112.
  18. Newmark HL. “Squalene, olive oil, and cancer risk: Review and hypothesis”. Annals of the New York Academy of Sciences1 (1999): 193-203.
  19. Goldbloom RB. “Studies of tocopherol requirements in health and disease”. Pediatrics 1 (1963): 36-46.
  20. Wagner K-H., et al. “Gamma-Tocopherol - An underestimated vitamin?” Annals of Nutrition and Metabolism3 (2004): 169-188.
  21. Dietrich M., et al. “Does γ-Tocopherol play a role in the primary prevention of heart disease and cancer? A review”. Journal of the American College of Nutrition4 (2004): 292-299.
  22. White E., et al. “Correlates of serum α- and γ-tocopherol in the women's health initiative”. Annals of Epidemiology2 (2001): 136-144.
  23. Mathur P., et al. “Tocopherols in the prevention and treatment of atherosclerosis and related cardiovascular disease”. Clinical Cardiology9 (2015): 570-576.
Citation: RE Carlson and JA von Fraunhofer. “Olive Oil: Nature’s Panacea”. EC Nutrition 17.6 (2022): 17-22.

PubMed Indexed Article


EC Pharmacology and Toxicology
LC-UV-MS and MS/MS Characterize Glutathione Reactivity with Different Isomers (2,2' and 2,4' vs. 4,4') of Methylene Diphenyl-Diisocyanate.

PMID: 31143884 [PubMed]

PMCID: PMC6536005


EC Pharmacology and Toxicology
Alzheimer's Pathogenesis, Metal-Mediated Redox Stress, and Potential Nanotheranostics.

PMID: 31565701 [PubMed]

PMCID: PMC6764777


EC Neurology
Differences in Rate of Cognitive Decline and Caregiver Burden between Alzheimer's Disease and Vascular Dementia: a Retrospective Study.

PMID: 27747317 [PubMed]

PMCID: PMC5065347


EC Pharmacology and Toxicology
Will Blockchain Technology Transform Healthcare and Biomedical Sciences?

PMID: 31460519 [PubMed]

PMCID: PMC6711478


EC Pharmacology and Toxicology
Is it a Prime Time for AI-powered Virtual Drug Screening?

PMID: 30215059 [PubMed]

PMCID: PMC6133253


EC Psychology and Psychiatry
Analysis of Evidence for the Combination of Pro-dopamine Regulator (KB220PAM) and Naltrexone to Prevent Opioid Use Disorder Relapse.

PMID: 30417173 [PubMed]

PMCID: PMC6226033


EC Anaesthesia
Arrest Under Anesthesia - What was the Culprit? A Case Report.

PMID: 30264037 [PubMed]

PMCID: PMC6155992


EC Orthopaedics
Distraction Implantation. A New Technique in Total Joint Arthroplasty and Direct Skeletal Attachment.

PMID: 30198026 [PubMed]

PMCID: PMC6124505


EC Pulmonology and Respiratory Medicine
Prevalence and factors associated with self-reported chronic obstructive pulmonary disease among adults aged 40-79: the National Health and Nutrition Examination Survey (NHANES) 2007-2012.

PMID: 30294723 [PubMed]

PMCID: PMC6169793


EC Dental Science
Important Dental Fiber-Reinforced Composite Molding Compound Breakthroughs

PMID: 29285526 [PubMed]

PMCID: PMC5743211


EC Microbiology
Prevalence of Intestinal Parasites Among HIV Infected and HIV Uninfected Patients Treated at the 1o De Maio Health Centre in Maputo, Mozambique

PMID: 29911204 [PubMed]

PMCID: PMC5999047


EC Microbiology
Macrophages and the Viral Dissemination Super Highway

PMID: 26949751 [PubMed]

PMCID: PMC4774560


EC Microbiology
The Microbiome, Antibiotics, and Health of the Pediatric Population.

PMID: 27390782 [PubMed]

PMCID: PMC4933318


EC Microbiology
Reactive Oxygen Species in HIV Infection

PMID: 28580453 [PubMed]

PMCID: PMC5450819


EC Microbiology
A Review of the CD4 T Cell Contribution to Lung Infection, Inflammation and Repair with a Focus on Wheeze and Asthma in the Pediatric Population

PMID: 26280024 [PubMed]

PMCID: PMC4533840


EC Neurology
Identifying Key Symptoms Differentiating Myalgic Encephalomyelitis and Chronic Fatigue Syndrome from Multiple Sclerosis

PMID: 28066845 [PubMed]

PMCID: PMC5214344


EC Pharmacology and Toxicology
Paradigm Shift is the Normal State of Pharmacology

PMID: 28936490 [PubMed]

PMCID: PMC5604476


EC Neurology
Examining those Meeting IOM Criteria Versus IOM Plus Fibromyalgia

PMID: 28713879 [PubMed]

PMCID: PMC5510658


EC Neurology
Unilateral Frontosphenoid Craniosynostosis: Case Report and a Review of the Literature

PMID: 28133641 [PubMed]

PMCID: PMC5267489


EC Ophthalmology
OCT-Angiography for Non-Invasive Monitoring of Neuronal and Vascular Structure in Mouse Retina: Implication for Characterization of Retinal Neurovascular Coupling

PMID: 29333536 [PubMed]

PMCID: PMC5766278


EC Neurology
Longer Duration of Downslope Treadmill Walking Induces Depression of H-Reflexes Measured during Standing and Walking.

PMID: 31032493 [PubMed]

PMCID: PMC6483108


EC Microbiology
Onchocerciasis in Mozambique: An Unknown Condition for Health Professionals.

PMID: 30957099 [PubMed]

PMCID: PMC6448571


EC Nutrition
Food Insecurity among Households with and without Podoconiosis in East and West Gojjam, Ethiopia.

PMID: 30101228 [PubMed]

PMCID: PMC6086333


EC Ophthalmology
REVIEW. +2 to +3 D. Reading Glasses to Prevent Myopia.

PMID: 31080964 [PubMed]

PMCID: PMC6508883


EC Gynaecology
Biomechanical Mapping of the Female Pelvic Floor: Uterine Prolapse Versus Normal Conditions.

PMID: 31093608 [PubMed]

PMCID: PMC6513001


EC Dental Science
Fiber-Reinforced Composites: A Breakthrough in Practical Clinical Applications with Advanced Wear Resistance for Dental Materials.

PMID: 31552397 [PubMed]

PMCID: PMC6758937


EC Microbiology
Neurocysticercosis in Child Bearing Women: An Overlooked Condition in Mozambique and a Potentially Missed Diagnosis in Women Presenting with Eclampsia.

PMID: 31681909 [PubMed]

PMCID: PMC6824723


EC Microbiology
Molecular Detection of Leptospira spp. in Rodents Trapped in the Mozambique Island City, Nampula Province, Mozambique.

PMID: 31681910 [PubMed]

PMCID: PMC6824726


EC Neurology
Endoplasmic Reticulum-Mitochondrial Cross-Talk in Neurodegenerative and Eye Diseases.

PMID: 31528859 [PubMed]

PMCID: PMC6746603


EC Psychology and Psychiatry
Can Chronic Consumption of Caffeine by Increasing D2/D3 Receptors Offer Benefit to Carriers of the DRD2 A1 Allele in Cocaine Abuse?

PMID: 31276119 [PubMed]

PMCID: PMC6604646


EC Anaesthesia
Real Time Locating Systems and sustainability of Perioperative Efficiency of Anesthesiologists.

PMID: 31406965 [PubMed]

PMCID: PMC6690616


EC Pharmacology and Toxicology
A Pilot STEM Curriculum Designed to Teach High School Students Concepts in Biochemical Engineering and Pharmacology.

PMID: 31517314 [PubMed]

PMCID: PMC6741290


EC Pharmacology and Toxicology
Toxic Mechanisms Underlying Motor Activity Changes Induced by a Mixture of Lead, Arsenic and Manganese.

PMID: 31633124 [PubMed]

PMCID: PMC6800226


EC Neurology
Research Volunteers' Attitudes Toward Chronic Fatigue Syndrome and Myalgic Encephalomyelitis.

PMID: 29662969 [PubMed]

PMCID: PMC5898812


EC Pharmacology and Toxicology
Hyperbaric Oxygen Therapy for Alzheimer's Disease.

PMID: 30215058 [PubMed]

PMCID: PMC6133268


News and Events


September Issue Release

We always feel pleasure to share our updates with you all. Here, notifying you that we have successfully released the September issue of respective journals and the latest articles can be viewed on the current issue pages.

Submission Deadline for Upcoming Issue

ECronicon delightfully welcomes all the authors around the globe for effective collaboration with an article submission for the upcoming issue of respective journals. Submissions are accepted on/before October 14, 2022.

Certificate of Publication

ECronicon honors with a "Publication Certificate" to the corresponding author by including the names of co-authors as a token of appreciation for publishing the work with our respective journals.

Best Article of the Issue

Editors of respective journals will always be very much interested in electing one Best Article after each issue release. The authors of the selected article will be honored with a "Best Article of the Issue" certificate.

Certifying for Review

ECronicon certifies the Editors for their first review done towards the assigned article of the respective journals.

Latest Articles

The latest articles will be updated immediately on the articles in press page of the respective journals.