Research Article
Volume 12 Issue 11 - 2021
HCV Antibody, Patient Therapy and Ocular Tissue Donation: Is a Review of Donor Criteria Warranted
Ellen Heck1,2,3*, Alison Dingrando3*, Lisa Juliano4 and H Dwight Cavanagh2*
1Department of Surgery, UT Southwestern Medical Center, Dallas, Texas, USA
2Department of Ophthalmology, UT Southwestern Medical Center, Dallas, Texas, USA
3Transplant Services Center, UT Southwestern Medical Center, Dallas, Texas, USA
4Collin College McKinney, Texas, USA
*Corresponding Author: Ellen Heck, Department of Surgery, UT Southwestern Medical Center, Dallas, Texas, USA.
Received: August 26, 2021; Published: October 27, 2021




Abstract

Hepatitis C serology reactivity in donors whose medical history does not suggest a reason for deferral continues to be of concern in ocular tissue availability. With the current treatments for Hepatitis C reporting cure of this often-occult disease it may now be time to consider if the Hepatitis C antibody only reactive donors might be acceptable for transplantation. This study reviews cases between May 2018 and May 2021 where screening, by Food and Drug Administration Regulation CR21 1271 and Eye Bank Association of America guidelines and standards, did not identify a cause for deferment of the donation. Sixty-two reactive serology donors with 20 reactive for Hepatitis C antibody only were identified in the 3660 donors during this interval. With a need to screen and defer donors for an increase in viral and other risk criteria, the ability to remove a potential, now possibly unnecessary, deferral reason could provide valuable tissues for corneal and other tissue transplants.

Keywords: Hepatitis C Antibody; Donor Screening; Tissue Availability

References

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Citation: Ellen Heck., et al. “HCV Antibody, Patient Therapy and Ocular Tissue Donation: Is a Review of Donor Criteria Warranted”. EC Ophthalmology 12.11 (2021): 08-14.

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