Case Report
Volume 9 Issue 3 - 2020
Guillain Barré Syndrome and Hepatitis A: A Case Report
FZ Sami1*, G Draiss1, N Rada1, Y Mouafeq2, S Younous2 and M Bouskraoui1
1Department of Pediatric A, CHU Mohamed VI, Marrakech, FMPM, Cadi Ayyad University, Morocco
2Department of Anesthesia Pediatric Ressuscitation, CHU Mohamed VI, Marrakech, FMPM, Cadi Ayyad University, Morocco
*Corresponding Author: FZ Sami, Department of Pediatric A, CHU Mohamed VI, Marrakech, FMPM, Cadi Ayyad University, Morocco.
Received: December 30, 2019; Published: February 06, 2020




Abstract

Introduction: Guillain Barré syndrome (GBS) is an acute demyelinating polyradiculoneuropathy rare in pediatrics. The association between confirmed viral hepatitis A and GBS is extremely rare; 18 cases which are described in the literature.

Objective of the Work: Emphasize this rare association as well as add another case to the 18 cases described in the literature through an observation collected at the pediatrics A department of CHU Mohamed VI in Marrakech and review of the literature.

Observation: He is a 9-year-old child from a non-consanguineous marriage with a history of hepatitis A confirmed by the positivity of the antibody against hepatitis A type IgM; occurred 8 days before symptomatology.

The patient was admitted for ascending quadriplegia associated with swallowing disorders and respiratory distress. The initial clinical examination objectified a peripheral motor deficit with abolished ROTs and major respiratory distress. The child was initially admitted to the intensive care unit or was intubated and tracheotomized. The lumbar puncture had objectified an albumino-cytological dissociation and the EMG was in favor of a severe acute polyradiculoneuritis.

The management consisted in the administration of intravenous immunoglobulins as well as 5 plasma exchange sessions.

The recovery phase was very gradual with almost complete healing thanks to motor physiotherapy.

Conclusion: The association of hepatitis A and GBS is extremely rare in the pediatric population and incites the vigilance of doctors before any neurological sign occurring during the surveillance of infections by viral hepatitis A.

Keywords: Guillain-Barré syndrome (GBS); Polyradiculoneuropathy; Hepatitis A

References

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  5. Deepak M., et al. “Guillain-Barré syndrome following acute viral hepatitis”. Journal of Neurosciences in Rural Practice 5.2 (2014): 204-205.
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  7. Brunschwig C., et al. “Syndrome de Guillain-Barré compliquant une hépatite A”. Médecine et Maladies Infectieuses 25 (1995): 1217-1218.
  8. Xie J., et al. “Guillain-Barre syndrome and hepatitis A. Lack of association during a major epidemic”. Annals of Neurology 24 (1988): 697-698.
  9. Ivan Baltadzhiev., et al. “Guillain-Barré syndrome in a Child with Ongoing Viral Hepatitis A Iran”. Journal of Child Neurology 12.3 (2018): 133-138.
  10. Saito M., et al. “All Guillain-Barré syndrome associated with acute hepatitis A-A case report and literature review Rinsho Shinkeigaku”. Clinical Neurology 58.9 (2018): 574-577.
  11. Bae YJ., et al. “A case of acute hepatitis a complicated by Guillain-Barré syndrome”. The Korean Journal of Hepatology 2 (2007): 228-233.
Citation: FZ Sami., et al. “Guillain Barré Syndrome and Hepatitis A: A Case Report”. EC Paediatrics 9.3 (2020): 01-04.

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