Case Series
Volume 10 Issue 8 - 2021
Toddlers with a Rare Cause of Failure to Thrive
Nitika Gautam1, Purnima Prabhu2 and Suhas V Prabhu3*
1Clinical Resident, Department of Pediatrics, P.D. Hinduja Hospital and Medical Research Centre, Mahim, Mumbai, India
2Pediatric Nutrition Therapist, Department of Pediatrics, P.D. Hinduja Hospital and Medical Research Centre, Mahim, Mumbai, In
3Consultant Pediatrician, Department of Pediatrics, P.D. Hinduja Hospital and Medical Research Centre, Mahim, Mumbai, India
*Corresponding Author: Suhas V Prabhu, Consultant Pediatrician, Department of Pediatrics, P.D. Hinduja Hospital and Medical Research Centre, Mahim, Mumbai, India.
Received: April 22, 2021; Published: July 31, 2021


Abetalipoproteinemia is a rare disorder of lipoprotein metabolism resulting in deficient production of apolipoproteins. As these children have fat malabsorption, they develop diarrhea and present with failure to thrive early in life. Improvement is seen with dietary intervention but poor long-term compliance with a difficult diet can lead to recurrence of symptoms. We describe four children who presented in late infancy with similar features. In all cases, hypocholesterolemia was present. With that clue, lipoprotein electrophoresis was performed which established the diagnosis. Starting on a diet rich in medium chain triglycerides and high oral doses of fat-soluble vitamins resulted in clinical improvement.

 Keywords: Malabsorption; Failure to Thrive; Abetalipoproteinemia; Chronic Diarrhea


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Citation: Suhas V Prabhu., et al. “Toddlers with a Rare Cause of Failure to Thrive”. EC Paediatrics 10.8 (2021): 82-88.

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