Review Article
Volume 10 Issue 12 - 2021
A Multicentric, Randomized, Double Dummy Study to Evaluate Therapeutic Dose Efficacy of Enoxaparin Versus Apixaban in Hospitalize Double Blind, D Covid-19 Patients
Ahmed Abdalla Bashir*, Prafulla Bhad, Owoicho Adogwa, Afoke Kokogho, Devendranath Reddy Mannuru, Luisa Mendonca and Yuping Xia
Pediatrics, Genetics, Clinical Studies Scientist, Al Mana Group, Saudi Arabia and UCLA, USA
*Corresponding Author: Ahmed Abdalla Bashir, Pediatrics, Genetics, Clinical Studies Scientist, Al Mana Group, Saudi Arabia and UCLA, USA.
Received: August 02, 2021; Published: November 18, 2021




Abstract

SARS-Co-2 is a novel human infectious single-stranded enveloped RNA virus. Patients will present with fever, cough, fatigue and pneumonia of varying severity. CDC report dated July 4, 2020 showed > 6.5 million cases globally, in more than 180 countries. Fatal outcomes are in > 65 years patients. 31% of the patients have increased risk of thromboembolic phenomenon (TE), 50% with poor prognosis if has elevated D-Dimmer, 13 - 69% develops venous thrombosis. This study planned to assess the therapeutic doses of enoxaparin versus apixaban in hospitalized patients with COVID-19 result in reduction of in arterial or venous thromboembolic events on top of institutional COVID-19 therapy as primary goal. In secondary goals, we will compare the survival rate, time to event, time to ICU admission, time to discharge, and safety between the two groups.

Keywords: SARS-Co-2; Thromboembolic Phenomenon (TE); COVID-19

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Citation: Ahmed Abdalla Bashir., et al. “A Multicentric, Randomized, Double Dummy Study to Evaluate Therapeutic Dose Efficacy of Enoxaparin Versus Apixaban in Hospitalize Double Blind, D Covid-19 Patients”. EC Paediatrics 10.12 (2021): 27-32.

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