Research Article
Volume 11 Issue 4 - 2022
Clinical Profile and Outcome of Pediatric COVID-19 Patients
Faruk Ahmed1*, ANM Shahidul Islam Bhuiyan2, Khondakar Zahirul Hasan1, Mohammad Monir Hossain3 and Mohammad Khairuzzaman4
1Assistant Professor, Department of Pediatrics, Abdul Malek Ukil Medical College (AMUMC), Noakhali, Bangladesh
2Assistant Professor, Department of Pediatrics, Cumilla Medical College, Cumilla, Bangladesh
3Assistant Professor, Department of Pediatrics, M. A. G. Osmani Medical College, Sylhet, Bangladesh
4Assistant Professor, Department of Pediatrics, Cox’s Bazar Medical College, Cox’s Bazar, Bangladesh
*Corresponding Author: Faruk Ahmed, Assistant Professor, Department of Pediatrics, Abdul Malek Ukil Medical College (AMUMC), Noakhali, Bangladesh.
Received: March 23, 2022; Published: March 31, 2022




Abstract

Introduction: Coronavirus complaint (COVID-19) is a severe acute respiratory contagious complaint coronavirus 2 (SARS-CoV2) infection in children manifests as mild to moderate complaint with low casualty. There's limited information about vulnerability to SARS CoV-2 infection, clinical profile and outgrowth among immunocompromised children in Bangladesh.

Objective: To assess the clinical findings and outcome of paediatric patients with confirmed COVID-19 positivity.

Materials and Methods: This observational study was carried out at the Department of Pediatrics, 250 Bed General Hospital, Gopalganj, Bangladesh from October 2020 to March 2021. The inclusion criteria were Patients aged day 1 to 15 years, and all patients confirmed Covid-19 positive by reverse transcription polymerase chain reaction (RT-PCR). Finally, 56 patients were enrolled in this study. The medical data was analyzed from previously taken questionnaire for each patient. Demographic data, medical history, contact history was included in the questionnaire.

Results: Fifty six patients were included in the study over a period of six months. Mean age was 59.96 ± 43.24 months, 48.2% were male and 51.8% were female. Among fifty six RT-PCR positive cases, thirty seven (66%) were symptomatic and Nineteen (34%) were asymptomatic. Patients got admitted with fever (44.6%), cough (25%), diarrhoea (12.5%), Nausea and vomiting (10.7%). Out of nineteen cases 33.9% were admitted for less than 10 days, 44.6% were admitted for 10 - 14 days and 21.4% were admitted for more than 14 days. Fifteen (26.7%) children were associated with co-morbid conditions like congenital heart disease (10.7%) followed by bronchial asthma, hereditary hemolytic anaemia, adenoid and ROP. 17.8% patient's had leucopenia, 12.5% lymphopenia and raised CRP, patients had, 12.8% patient had neutrophilia. There was Serum Ferritin high in only 7.1% cases. Our study 30.3% patients had normal Chest X-Ray and mild lesion 57.1%, bilateral consolidation 8.9% and 3.5% patchy opacities and six cases eight (14%) cases had positive CRP. Out of the fifty six cases three (5.3%) cases had high S. creatinine level with a mean of 0.47 ± 0.19 mg/dl and seven (12.5%) cases had high S. procalcitonin level with mean procalcitonin level was 0.0656 ± 0.4 ng/ml. Chest X-ray was done in all cases and in all cases these were normal, therefore no HRCT chest was done. Out of all fifty patient 55 patients were improved and discharged. Only one child died in this cohort.

Conclusion: In a significant proportion of children, COVID-19 infection has an asymptomatic course, which contributes greatly to the spread of the complaint. Clinical profile of COVID 19 in children was mild and the outgrowth was good. Fever and cough were the predominant findings of COVID-19 affected children in this study. While COVID-19 causes morbidity similar as storms in the paediatric population, the complaint had a more severe course in children with an underpinning serious complaint and may indeed affect in death.

 

Keywords: COVID-19; Children; SARS-CoV-2; Outcome

References

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Citation: Faruk Ahmed., et al. “Clinical Profile and Outcome of Pediatric COVID-19 Patients”. EC Paediatrics 11.4 (2022): 133-139.

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