Research Article
Volume 6 Issue 4 - 2021
Age Prediction for COVID-19 Suspects and Contacts in Villa Clara Province, Cuba
Ricardo Osés Rodríguez1, Claudia Osés Llanes2, Rigoberto Fimia-Duarte3,4*, Alfredo González Meneses5, José Iannacone6,7, Thaináh Bruna Santos8 and Fran M Wilford González4
1Provincial Meteorological Center of Villa Clara, Cuba
2Department of Hygiene and Epidemiology, XX Anniversary Policlinical, Santa Clara, Villa Clara, Cuba
3Faculty of Health Technology and Nursing (FTSE), University of Medical Sciences of Villa Clara (UCM-VC), Cuba
4Career of Veterinary Medicine and Zootechnics, Faculty of Agricultural Sciences (FCA), Central University “Marta Abreu” of Las Villas, Cuba
5Construction Enterprise of the Electric Industry of Villa Clara, Cuba
6Laboratory of Animal Ecology and Biodiversity (LEBA), Faculty of Natural Sciences and Mathematics (FCNNM), Federico Villarreal National University (UNFV), The Agustino, Lima, Peru
7Faculty of Biological Sciences. Ricardo Palma University (URP), Santiago de Surco, Lima,Peru
8San Gregory University of Portoviejo, Portoviejo, Manabí, Ecuador
*Corresponding Author: Rigoberto Fimia-Duarte, Faculty of Health Technology and Nursing (FTSE), University of Medical Sciences of Villa Clara (UCM-VC), Cuba.
Received: February 17, 2021; Published: March 23, 2021


The COVID-19 pandemic affecting planet Earth has had a peculiar development in Cuba. The objective of the research consisted in modeling by means of the methodology of the Regressive Objective Regression (ROR) two parameters/variables (age and number of contacts) inherent to the SARS-CoV-2 pandemic causing the COVID-19, during the year 2020 and so far in 2021 in Villa Clara province, Cuba. Mathematical models were obtained by means of the ROR methodology that explain their behavior, being able to extract information from a white noise, which made it possible to make a long-term prognosis of contact cases, which can be estimated up to 13 steps ahead, allowing to take measures in clinical services, and thus avoid and decrease the number of deaths and complications in patients, since patients can be detected and treated with medication faster. The age of suspects can also be estimated using the ROR methodology, where the trend of age was increasing for contact cases, where all variables were significant, indicating that there is an increasing tendency for cases to decrease if control measures are increased. It is concluded that COVID-19, despite being a new disease, can be followed by means of mathematical modeling ROR, a better management of the pandemic, so we hope that this prognosis can help in decision making for the prediction age, suspects and contacts of COVID-19 in the Villa Clara province and Cuba.


Keywords: COVID-19; Age; Prognosis; Objective Regression Regression (ORR); Suspects


  1. Metcalf CL and Flint RL. “Insectos destructivos e insectos útiles”. 2nd La Habana. Pueblo y Educación (1975).
  2. Kyle JL and Harris E. “Global spread and persistence of dengue”. Annual Review Microbiology 62 (2008): 71-92.
  3. Troyo A., et al. “Seasonal profiles of Aedes aegypti (Diptera: Culicidae) larval habitats in an urban area of Costa Rica with a history of mosquito control”. Journal of Vector Ecology 33 (2008): 76-88.
  4. WHO (World Health Organization). “Dengue y dengue hemorrágico. Nota descriptiva N- 117. Revisión de mayo 2008”. WHO (2009).
  5. Cassab A., et al. “Factores climáticos y casos de dengue en Montería, Colombia. 2003-2008”. Rev Salud Pública de Colombia 13 (2011): 1-12.
  6. Maron GM., et al. “Characterization of Dengue Shock in pediatric patients in The Salvador”. The Pediatric Infectious Disease Journal 30 (2011): 449-450.
  7. Delatte H., et al. “Geographic distribution and developmental sites of Aedes albopictus (Diptera: Culicidae) during a Chikungunya epidemic event”. Vector- Borne and Zoonotic Diseases 8 (2008): 25-34.
  8. Dehecq JS., et al. “The re-emergence of the chikungunya virus in Reunion Island on 2010. Evaluation of the mosquito control practices”. Le Bulletin de la Société de Pathologie Exotique 2 (2011): 153-160.
  9. Lugones BM and Ramírez BM. “Dengue”. Revista Cubana de Medicina General Integral 28 (2012): 1-4.
  10. Gould E., et al. “Emerging arboviruses: why today?”. One Health 4 (2017): 1-13.
  11. Fimia DR., et al. “Factores antropogénicos y ambientales sobre la fauna de culícidos (Diptera: Culicidae) de la provincia Sancti Spíritus, Cuba”. The Biologist 13 (2015): 41-51.
  12. Berovides V and Gerhartz JL. “Diversidad de la vida y su conservación”. Editorial Científico Técnica (2007): 98.
  13. Sun Z., et al. “Potential Factors Influencing Repeated SARS Outbreaks in China”. International Journal of Environmental Research and Public Health 17 (2020): 1633.
  14. Huang C., et al. “Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China”. The Lancet 395 (2020): 497-506.
  15. Singhal T. “A Review of Coronavirus Disease-2019 (COVID-19)”. The Indian Journal of Pediatrics 87 (2020): 281-286.
  16. Yi Y., et al. “COVID-19: what has been learned and to be learned about the novel coronavirus disease”. International Journal of Biological Sciences 16 (2020): 1753-1766.
  17. Fang J., et al. “Review of the clinical characteristics of Coronavirus Disease 2019 (COVID-19)”. The Journal of General Internal Medicine (2020).
  18. Wu Z and Mc Googan JM. “Characteristics of and importantles sons from the coronavirus disease 2019 (COVID-19) outbreak in China: Summary of a report of 72 314 cases from the Chinese center for disease control and prevention”. The Journal of the American Medical Association (2020a).
  19. Wu, F., et al. “Severe acute respiratory syndrome coronavirus 2 isolate Wuhan-Hu-1, complete genome”. Nature 579 (2020b): 265-269.
  20. WHO (World Health Organization). “Draft land scape of COVID-19 candidate vaccines”. WHO (2020).
  21. Fan Y., et al. “Bat Coronaviruses in China”. Viruses 11 (2019): 1-14.
  22. Wang BX and Fish EN. “Global virus st outbreaks: Interferons as 1 responder”. Seminars in Immunology 43 (2019): 101300.
  23. Woo PCY and Lau SKP. “Viruses and Bats”. Viruses 11 (2019): 880-884.
  24. Ivorra B and Ramos AM. “Validation of the forecasts for the international spread of the coronavirus disease 2019 (COVID-19) done with the Be-CoDiS mathematical model”. Reporte Técnico Grupo MOMAT, Universidad Complutense de Madrid (2020): 1-14.
  25. Osés RR., et al. “Regressive methodology (ROR) VERSUS Genetic Code in mutations of VIH”. International Journal of Agriculture Innovations and Research 3 (2015a): 2319-1473.
  26. Osés RR., et al. “Climatic impact of the temperature in the presence of cold avian infections in Cuba”. International Journal of Development Research 5 (2015b).
  27. Osés RR., et al. “Modelación matemática del cólera por medio de la Regresión Objetiva Regresiva y su relación con las variables climáticas en Caibarién, Villa Clara, Cuba”. The Biologist (Lima) 15 (2017c).
  28. Sánchez ÁML., et al. “La Regresión Objetiva Regresiva más allá de un ruido blanco para los virus que circulan en la provincia Villa Clara, Cuba”. The Biologist (2017):1.
  29. Osés R and Grau R. “Modelación regresiva (ROR), versus modelación ARIMA usando variables dicotómicas en mutaciones del VIH”. Editorial Feijóo (2011).
  30. Osés RR., et al. “Modelación de la densidad larvaria total de mosquitos (Diptera: Culicidae) utilizando tres modelos en la provincia de Villa Clara, Cuba”. REDVET 15 (2014).
  31. Osés RR., et al. “Modelación y predicción de la fasciolosis en Villa Clara, Cuba”. BIOTEMPO (Lima) 14 (2017a): 27-34.
  32. Osés RR., et al. “The ROR's methodology an it's possibility to find information in a white noise”. International Journal of Current Research 9 (2017b): 47378-47382.
  33. Osés RR., et al. “Modelación ROR aplicada a pronósticos”. Editorial Académica Española (eae). Editorial de Omni Scriptum Publishing KS. Brivibas gatve 197, Riga, LV-1039 Latvia, European Union (2019).
  34. Osés RR., et al. “Prognosis of COVID-19 through Regressive Objective Regression methodology in Villa Clara and Cuba”. The Biologist 18 (2020): 171-184.
  35. Fimia DR., et al. “Modelación y predicción hasta el año 2020 para la angiostrongilosis total utilizando la Regresión Objetiva Regresiva. Villa Clara, Cuba”. The Biologist 15 (2017a).
  36. Fimia DR., et al. “Modelación y predicción de las Infecciones Respiratorias Agudas (IRA) utilizando las variables climáticas en la provincia Villa Clara, Cuba”. The Biologist 15 (2017b).
Citation: Rigoberto Fimia-Duarte., et al. “Age Prediction for COVID-19 Suspects and Contacts in Villa Clara Province, Cuba”. EC Veterinary Science 6.4 (2021): 41-51.

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