Research Article
Volume 6 Issue 8 - 2021
Hypolipidemic Activities and Nutritive Values of Brassica napus and Eruca sativa Seed Supplementation in Rats Fed a High Cholesterol Diet
Sorial A Moharib*
Biochemistry Department, National Research Centre, Dokki, Cairo, Egypt
*Corresponding Author: Sorial A Moharib, Biochemistry Department, National Research Centre, Dokki, Cairo, Egypts.
Received: July 08, 2021; Published: August 28, 2021


The present study concerns the use of rapeseed (Brassica napus) and watercress (Eruca sativa) seeds commonly major consumed vegetables in food items as natural source of diets. To examine their effects on growth rate, nutritive values hypocholesterolemic diet fed rats, lipidemic, two groups of seven adult male albino rats were fed high-cholesterol diet supplements with 100 g/kg rapeseed (Brassica napus) and watercress (Eruca sativa) seeds (HCD-R and HCD-W respectively) for 8 weeks compared to high-cholesterol diet fed rats (HCD). Chemical analyses of the rapeseed (R) and watercress (W) seeds revealed differences between the ratios of protein (20 - 23%), lipid (28 - 33%), carbohydrate (36 - 43%) and phenolic constituents (2 - 3%). Rats fed with both experimental diets containing 100 g/kg diet of R and W seeds (HCD-R and HCD-W respectively), exhibited a higher significant increase in body weight gain, food intake and digestibility (Dapp) throughout the feeding period (2 - 8 weeks). Insignificant changes in feed efficiency (FE) and food conversion efficiency (FCE) were observed. Both experimental diets (HCD-R and HCD-W) evidence lowering effects in the levels of total lipids, total cholesterol, LDL-C and triglycerides in sera of rat as compared to control diet fed rats (HCD). The HCD-R and HCD-W diet (100 g/kg) had also a lowering effect on hepatic total lipids, total cholesterol, triglycerides and cholesterol ester levels. Highly significant increase in HDL-C was observed in the liver of rats fed HCD-R diet than those received HCD-W and HCD fed rats. According to these observations, the use of rapeseed (Brassica napus) and watercress (Eruca sativa) seeds can be recommended as natural sources for improving nutritional values of food supplements used as hypolipidemic agent and may be treated heart and cancer diseases.

Keywords: Rapeseed; Watercress Seeds; Polyphenol; Hypercholesterolemic; Rat


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Citation: Sorial A Moharib. “Hypolipidemic Activities and Nutritive Values of Brassica napus and Eruca sativa Seed Supplementation in Rats Fed a High Cholesterol Diet”. EC Veterinary Science 6.9 (2021): 29-40.

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