Dr. Dorothea Thompson is presently an Associate Professor in the Department of Pharmaceutical Sciences at Campbell University, where he teaches primarily Medical Microbiology and Immunology in the Doctor of Pharmacy program. Prior to joining the faculty at Campbell University, He was a Ph.D.-level research scientist working at the U.S. Department of Energy’s Oak Ridge National Laboratory (ORNL) in Oak Ridge, TN and a faculty member in the Department of Biological Sciences at Purdue University (West Lafayette, IN). While at ORNL, my research focus was in the area of microbial functional genomics, specifically the application of DNA microarray profiling and two-dimensional high-performance liquid chromatography-tandem mass spectrometry to elucidating metal stress regulation in such environmentally important bacteria as Shewanellaoneidensis and Pseudomonas putida. As an Assistant Professor of Microbiology at Purdue University, he collaborated with biospectroscopists to develop and apply a Raman chemical imaging platform using functionalized nanoprobes to chemically map subcellular metal bioreduction sites in bacteria. Previous research also includesidentification and functional characterization of an S. oneidensis two-component response regulator involved in siderophore-mediated iron acquisition and the development of a genotyping system for pathogenic Neisseria gonorrhoeae based on biotinylated oligonucleotide probes to porin gene variable regions.
Dr. Dorothea Thompson’s research interests include the identification of risk factors associated with the increasing rate of septicemia in a hospital population in a rural county in North Carolina. In addition to case-control studies in infectious disease, other research interests focus on the development of biomarkers for microbial stress response and metal detoxification.
Bacteriology; Gene expression regulation; Functional genomics (e.g., transcriptomics and proteomics) and Stress response pathways in bacteria.