Dr. Russell W. Hanson is an Assistant Professor at the Mount Sinai School of Medicine and the Institute for Genomics and Multiscale Biology. His lab has been focusing on new methods to use bioinformatics and sequencing data for personalized medicine and stratified medicine. They have developed novel techniques using nanoparticles, imaging, and data-driven immunology. By applying the extensive and validated biomarkers from GWAS studies in a targeted, actuated, and specific fashion they are building new methods in mRNA therapeutics, synthetic biomarkers, synthetic biology, and MR and CT imaging.
His academic background in physics, chemistry and physical chemistry, genetics and biology, and informatics make this multidisciplinary research compelling. They have assembled a skilled team with experience in ligand-based assays, drug discovery and biochemistry as well as the necessary nanoparticle treatment and physics imaging methods. On the informatics side he contributed to large scale research projects spanning over 35,000 individuals at high-density single nucleotide polymorphism (SNP) resolution, developed databases of epitopes for immunotherapy, and determined Human Leukocyte Antigen (HLA) subtypes that are resistant and sensitive to several cancer subtypes (OncoImmunology, 2012).
In addition to his academic background, he is having many years of experience in the high technology industry. The demands in industry to create methods and technologies that are repeatable, scalable, and provide value to customers and investors have helped motivate his interest in developing robust technology platforms. He worked in drug discovery bioinformatics using the model organism Drosophila melanogaster, have developed automatic methods and algorithms generating significant returns, and more recently have developed and marketed informatics and machine learning methods for imaging cells (Reducible Systems, 2014).
Bioinformatics; Physics; Chemistry and Physical Chemistry; Genetics and Biology.