Dr. Pushpanathan Muthuirulan received his Ph.D., degree in Microbiology from Department of Genetics, School of Biological Sciences at Madurai Kamaraj University, India during 2014, where he identified a novel antifungal peptide, MMGP1 from marine environment using function-based metagenomic approach (Prot. Pept. Lett., 2012). The peptide has therapeutic potential to treat human infections such as Candidiasis and Aspergillosis. He used different computational tools and experimental approaches (using flow cytometry, confocal microscopy, etc) to characterize the unique mechanism of action of this peptide (J.Pept.Sci., 2012; Int. J. Pep.Res.Ther., 2012; Plos One, 2013; Mol.Pharma., 2016).After developing a healthy curiosity for the field of metagenomics, he went on using sequence-based metagenomic approach (16S rDNA sequencing, metagenome shotgun sequencing and metatranscriptome profiling) to understand the existence, diversity and role of microbial community associated with different environments (marine, termite gut, butter milk and blood of CVD patients) (IJM, 2012; CurrSci, 2014; Food Biotech, 2013; Plos One, 2014). With strong background in the areas of genomics, transcriptomics and proteomics, he joined NICHD at National Institutes of Health during 2014 and currently utilizing his adapted skills towards developing innovative strategies to map complex neural circuits underlying vision pathways in Drosophila.
Peptide chemistry; Protein engineering; Genomics; Transcriptomics; Molecular Biology and Bioinformatics.