Dr. Ioannis Papayannopoulos has been carrying out peptide and protein analysis and characterization work, using mass spectrometry, chromatography and other analytical techniques, for over a quarter century. He received his undergraduate degree in Chemistry from Bowdoin College and his PhD in Organic Chemistry from the Massachusetts Institute of Technology, where he conducted his research in mass spectrometry under the supervision of the late Professor Klaus Biemann. He has held senior scientific and management positions in the biopharmaceutical industry, at such companies as AstraZeneca, Biogen, EMD Pharmaceuticals and Targanox, and in academia, most recently as the director of the proteomics core facility at the Koch Institute for Integrative Cancer Research at MIT. Dr. Papayannopoulos is currently with Celldex Therapeutics, a biotechnology company in Massachusetts, working on the analysis and characterization of antibodies, antibody-drug conjugates and recombinant protein pharmaceuticals.
Dr. Papayannopoulos’ research interests have included understanding the issues, especially those related to sample preparation, which affect reproducibility in the acquisition of mass spectrometric data in protein characterization and proteomics work. He has also taken a keen interest in the development and application of bioinformatics tools for the standardization and comparison of protein characterization and proteomics results over time and across different laboratories and instrument platforms.