Dr. Nath is currently working as Research Assistant Professor at the University of Pennsylvania, Perelman School of Medicine, Department of Radiology, and Molecular Imaging Section. He did his Ph.D. from a premier medical research institute in India. During Ph.D. He applied diffusion weighted imaging and magnetic resonance spectroscopy (MRS) techniques to patients with various forms of liver failure, and brain abscess, brain tumor and neurocysticercosis. After completing Ph.D., He joined Moffitt Cancer Center at Tampa and was trained to analyze variance in PET imaging data. He then joined University of Pennsylvania and has been working on two NIH sponsored projects entitled “Systemic Chemotherapy of Melanoma: NMR Studies of Lonidamine & N-Mustard Activity” and “Mechanism of Activity of Lonidamine”. He quickly grasped the experimental aspects and began integrating MRS to determine the effects of lonidamine on energy production, lactate levels and pHi/pHe changes in melanoma and several carcinoma xenografts compared to the response of normal tissues (brain, live and skeletal muscle). Specifically, He seeks to employ the natural tendency of cancers to convert glucose to lactate as a method for selective intracellular acidification, which is known to potentiate tumor response to chemotherapy with N-mustard alkylating agents as well as hyperthermia and radiation therapy. He has been recognized with awards at several conferences he has attended. His work has been recognized by International Society for Magnetic Resonance in Medicine (ISMRM) as he has received the prestigious Magna Cum Laude award on multiple occasions. He has delivered several invited lectures at various institutions about the scope of his current research work. He has published 29 research articles in various reputed journals and presented more than 50 papers at various national and international scientific meetings.
Magnetic Resonance Imaging; Spectroscopy (MRI/MRS); Breast Cancer; Brain tumors; Prostate Cancer; Melanoma; Lymphoma; Radiation therapy; Chemotherapy; Hyperthermia.